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Antes Revista del Instituto Nacional de Enfermedades Respiratorias

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2010, Number 2

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Neumol Cir Torax 2010; 69 (2)

Renin/prorenin receptor and its relationship with idiopathic pulmonary fibrosis

Montes ME

Language: Spanish
References: 53
Page: 116-122
PDF size: 803.69 Kb.


ABSTRACT

The emergence of a new member of the renin-angiotensin system, the renin /prorenin receptor revealed an unexpected role of this system different to its classical in, the regulation of blood pressure. Recent evidences indicate that therenin/prorenin receptor could have an important role in extracellular matrix remodeling in several fibrosing disorders of kidney and heart. In this review we present the latest findings of the renin/prorenin receptor and its participation in fibrosing processes that may be relevant in the pathogenesis of idiopathic pulmonary fibrosis.


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