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1999, Number 3

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Enf Infec Microbiol 1999; 19 (3)

Pulmonary and pleural coccidioidomycosis treatment. Experience with six cases in Torreón, Coahuila

Padua AG, Martínez OV, Velasco RV, Calva MJJ, Cicero SR
Full text How to cite this article

Language: Spanish
References: 9
Page: 133-138
PDF size: 343.83 Kb.


Key words:

coccidioidomycosis, Coccidioides immitis, amphotericin, fluconazole, decortication, lung resection.

ABSTRACT

We present results of medical surgical treatment in six patients with coccidioidomycosis. Four patients had pulmonary disease and two pleural empyema. The treatment was selected in relation to the clinic radiological data of the patients. High-dose fluconazol was used for several months in chronic pneumonia cases. Amphotericine B was used in a patient with diseminated (miliar) pneumonia. Pleural cases were held up under medical and surgical treatment. Four patients cured, and were Coccidioides immitis-negative, another one continues asymptomatic and stable and was fungus-negative. Miliar case died. Coccidioidomycosis is similar to tuberculosis and must be differentiated by KOH 10% direct study, sputum mycologic culture, broncho-alveolar lavage or searching fungus in affected-tissue biopsy.


REFERENCES

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  6. Bronniman DA, Adam RD, Gagliani JN, et al. Coccidioidomicosis in the acquired immunodeficiency syndrome. Ann Intern Med 1987;106:372-9.

  7. Ampel NM, Dols CL, Gagliani JN. Coccidioidomicosis during human immunodeficiency virus infection: results of a prospective study in an endemic area. Am J Med 1993;94:235-40.

  8. Martínez J, Trujillo R, Padua A, González MR, Manríquez L. Coccidioidomicosis pulmonar. Tratamiento quirúrgico de dos casos. Gac Med Mex 1993;129:372-9.

  9. Bennet JE. Antifungal agents. En: The pharmacological basis of therapeutics. 9ª ed. Hartman JG, editor. New York: Mc Graw- Hill, 1996:1042-183.




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Enf Infec Microbiol. 1999;19