Flores-Carreras Ó, Martínez-Espinoza CJ, González-Ruiz MI, Montes-Casillas YE

Language: Spanish
References: 9
Page: 187-190
PDF size: 428.27 Kb.

ABSTRACT

Background: One of the characteristics of urinary symptoms in women is their lack of specificity. Patients with stress incontinence or urgency, local irritation, infection, distal stenosis or a neoplastic process have very similar symptoms.
Objective: Determine the frequency of bladder structural lesions detected by urethrocistoscopy in which we performed bladder biopsies.
Material and method: Descriptive, retrospective, analytical study of files and videos of 331 patients treated in Urodifem de Occidente (private Urogynecology Center). Thirty-five biopsies were taken. The statistical analysis was expressed as means standard deviations, ranges, percentages and Fishers test.
Results: Patients ages range 30-90 years average 60+13.76. Predominant symptoms were: irritative vesical syndrome 62.8%; pelvic pain 45.71%; urge incontinence 31.4%; hematuria 31.4%; vesical voiding dysfunction 11.4%. Principal endoscopic findings: Urethrotrigonitis; glomerular lesions or Hunner ulcers; vesical trabeculations; tumor or suspect lesions. Histopathologic findings were: Interstitial Cystitis 42.9%; chronic Cystitis 11.4%; Cystitis glandularis 8.6%; Cystitis follicular 11.4%; bladder cancer 5.7%; Vesical Papilloma 5.7%.
Conclusions: This study supports the practice of vesical biopsy when lesions other than those from chronic infection are observes in the presence of tumors or suspect lesions.

REFERENCES

1. Wu JM, Williams KS, Hundley AF, et al. Microscopic hematuria as a predictive factor for detecting bladder cancer and cystoscopy in women with irritative voiding symptoms. Amer J of Obstet Gynecol 2006;194:1423-1426.

2. National Cancer Institute. Surveillance. Epidemiology and end Results (Seer) Program . [Accessed Oct 20, 2005].

3. Jemal A, Murray T, Ward E, et al. Cancer Statistics 2005. CA Cancer J Clin 2005;55:10-30.

4. Cundiff GW, Bent AE. The contribution of urethrocystoscopy to evaluation of lower urinary tract dysfunction in women. Int Urogynecol J 1996;7:307-311.

5. Pashos CL, Botheman MF, Laskin BL, Redaelli A. Bladder cancer epidemiology, diagnosis and management. Cancer Pract 2002;10:311-322.

6. Borden LS, Clark PE, Hall MC. Bladder cancer. Curr Opinion Oncol 2003;15:227-233.

7. Sokoe ER, Patel SR, Sung VW, et al. Results of urine cytology testing and cystoscopy in women with irritative symptoms. Am J Obstet Gynecol 2005;192:1560-1565.

8. Bryan RT, Nicholls JH, Harrison RF, et al. The role of betacatenin signaling in the malignant potential of cystitis glandularis. J Urol 2003;170(S):1892-1896.

9. Sung MT, Lopez-Beltran A, Eble JN, et al. Divergent pathway of intestinal metaplasia and cystitis glandularis of the urinary bladder. Mod Pathol 2006;19(11):1395-1401.