2010, Number 4
Report on a cohort of 197 patients with papillary cancer of the thyroid operated at the Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán” (INCMNSZ) in Mexico City
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ABSTRACTObjective: The objective of the present study is to analyzethe characteristics of presentation, assessment and treatment of a cohort of 197 patients treated at our institution in 11 years (1992-2002). Setting: Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”, third level health care center.
Design: Observational, retrolective, transversal and descriptive study.
Statistical analysis: Descriptive statistics, estimating averages and standard deviation for continuous variables (level of thyroglobuline, TSH, etc.). Prevalence and frequency are expressed through sonography and pathology. The SPSSS 16.0 software was used.
Patients: Men and women older than 16 years, with a diagnosis of papillary carcinoma of the thyroid confirmed through pathology, treated at the INCMNSZ from June 1992 to May 2002. Variables: We gathered information on the clinical characteristics of the studied population, the histopathological features of the tumor, and the surgical treatment and evolution of the patient.
Conclusions: This review describes an increase, in our milieu, in the occurrence of differentiated tumors of the thyroid gland; this can probably be explained by the availability of new diagnostic methods that allow for an earlier and more efficient diagnosis, all constituting a known and compulsory part of the current algorithm for the management of this group of patients, as are ultrasound and preoperative biopsy. Total thyroidectomy seems to be the resection of choice, considering the multicentricity of the disease in our millieu (39%), with early and late complications comparable to those described in the literature in a high specialty center (2% hypothyroidism and dysphonia); even when performing ganglionary dissections of the affected compartments.
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