Ávila CMC

Language: Spanish
References: 0
Page: 12-15
PDF size: 43.38 Kb.

ABSTRACT

Apoptosis is one of the two normal mechanisms of cell death, also a need for tissue renovation. It is produced by partial ischemia, affects firstly the cell membrane, and then the nucleus, condensation of chromatin and fragmentation of DNA. There are genes that stimulate apoptosis as well as genes that diminish it. The study of the regulation of apoptosis has a great therapeutic potential, which could influence the elimination of tumors, reduce the “normal” neuronal loosing, the conservation of CD4 in AIDS or disappear auto-reactive cells in immune diseases. This cellular death mechanism is also important in the pathogenesis of all renal diseases, glomerular and tubular, and its entire comprehension and possible modification could change the usual treatments.