Acosta-Garduño J, Sánchez-Puente JC, Aragón-Tovar AR, Torres-Medina E, Vilchis-Cárdenas MA, Urbina-Bernal LC, Muñoz-Islas EI

Language: Spanish
References: 8
Page: 224-227
PDF size: 3728.65 Kb.

ABSTRACT

Radical cystectomy with urinary diversion is considered to be the treatment criterion standard for muscle-invasive bladder cancer. It is also indicated for stage T1 recurrent disease and carcinoma in situ that does not respond to chemotherapy or intravesical immunotherapy.
Objective: To determine radical cystectomy morbidity and mortality in a representative sample of the population of northeastern Mexico.
Methods: A retrospective study was carried out on 33 patients that underwent radical cystectomy during the time frame of September 2004 to July 2009. Surgical mortality or mortality secondary to the procedure as well as intraoperative morbidity and complication rate associated with surgical procedure were analyzed.
Results: Postoperative mortality rate was 0.06% in the first 60 days. Postoperative complication frequency was 33% and the most frequent complications were intestinal or urothelial anastomosis dehiscence (6% each one) and thromboembolic events (6%). The most frequent prior associated comorbidities were cardiovascular (18%), metabolic (15%) and respiratory (12%).
Discussion: Overall mortality rate after radical cystectomy is around 0.03% in different series. However, complication frequency after radical cystectomy varies from 25-35%. The results of the present study were similar to those published in different reports.
Conclusions: Given that bladder cancer in the muscleinvasive stage is a potentially lethal condition and that radical cystectomy has been associated with low mortality and acceptable morbidity rates, this procedure should be offered to all patients diagnosed with this condition who do not present with contraindications.

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