2010, Number 4
Camarena-Reynoso HR, Leos-Acosta C, Shuck-Bello CE, Hernández-Castellanos VA, Cantellano-Orozco M, Morales-Montor JG, Pacheco-Gahbler Carlos, Calderón-Ferro Francisco, Sotomayor-De Zavaleta Mariano
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ABSTRACTBackground: Peyronie’s disease is an acquired condition characterized by the formation of fibrous plaques in the tunica albuginea of the penis. The majority of patients can be managed conservatively with oral or intralesional medication. Surgical options vary from tunica albuginea shortening contralateral to the curvature, to resection of the fibrous area with graft application. One alternative is the use of porcine small intestine submucosa.
Objective: To demonstrate porcine intestinal submucosal graft application in the treatment of Peyronie’s disease.
Clinical case: Patient is a 66-year-old man with 9-year disease onset presenting with cephalic penile curvature accompanied by pain during erection. Test with alprostadil showed penile curvature and 2 cm dorsal plaque. Patient was treated with vitamin E and colchicine for 6 months with no improvement. The decision was made to apply porcine intestinal submucosal graft.
Conclusions: Porcine intestinal submucosa application is a useful alternative in treating Peyronie’s disease. It provides length and flexibility while correcting penile curvature by generating healthy cell growth at the fibrosis site, converting it into functional tissue. It is easy to rehydrate and suture, it minimizes scar tissue formation, and it is infection-resistant.