Flores-Carreras Ó, Martínez-Espinoza CJ, González-Ruiz MI

Language: Spanish
References: 10
Page: 125-130
PDF size: 526.53 Kb.

ABSTRACT

Background: The Interstitial Cystitis (IC) has been considered in the past an uncommon pathology, however it has received a special attention during the last 20 years, (1678 scientific articles published since 1984 to 2009). There are many therapeutic options not at all satisfactory because there isn't consensus about diagnostic and treatment.
Objective: To share our experiences in the treatment of interstitial cystitis, additionally, to comment on the therapeutic response of treatment used.
Material and method: Observational, retrospective an analytic study of 17 treated patients from 22 with diagnosis of IC and Bladder Painful Syndrome (IC/BPS) were managed in Urodifem de Occidente, S.C. a private Urogynecologic unit between January 2001 and April 2010. The diagnosis was done in agreement with the concepts of Interstitial Cystitis group from clinical and cystoscopic characteristics. The treatment was: Dimethyl sulfoxide (DIMSO) and Pentosan Polysulfate.
Results: The evaluation was measured by Interstitial Cystitis Symptomatic Index (ICSI) and Interstitial Cystitis Problem Index (ICPI) both validated evaluation instruments, 82% of the patients had a significative improvement of symptomatology and quality of live The ICSI pre and post treatment was of 17.0 and 4.5 and the ICPI was of 14.8 and 4.1 respectively.
Conclusion: We recommend the use of combine treatment of DIMSO and PPS in cases of I.C.

REFERENCES

1. Flores-Carreras O, González Ruiz MI, Martinez-Espinoza CJ, Calderon-Lara SA. Evaluación clínica y diagnóstica en pacientes con cistitis intersticial. Ginecol Obstet Mex 2010;78(5)275- 280.

2. Hano P, Dmochowiski. Status of International Consensus on Interstitial Cystitis/Bladder Pain Syndrome. Neurourol Urodynam 2009;28:274-286.

3. Christmas TJ. Historical aspects of Interstitial Cystitis. In: Sant GR (Ed) Interstitial Cystitis. Philadelphia: Lippincott-Raven, 1975;pp1-8.

4. Oravisto KJ. Epidemiology of interstitial cystitis. Ann Chir Gynaecol Fenn 1975;64:75-77.

5. Parsons JK, Kurth K, Sant GR. Epidemiologic issues in interstitial cystitis. Urology 2007;69:(Suppl. 4A):5-8.

6. Sant GR. Intravesical 50% dymethylsulfoxide (Rimso 50) in treatment of interstitial cystitis. Urology 1987;29(4 Suppl.): 17-21.

7. O’Leary MP, Sant GR, Fowler FJ, et al. The interstitial cystitis symptom index and problem index. Urology 1997;49(Suppl. 5A):58-63.

8. Perez-Marrero M, Emerson LE, Feltis JT. A control study of dymethylsulfoxide in Interstitial Cystitis. J Urol 1988;140:36-39.

9. Barker SB, Mathews PN, Philip PH, Williams G. Prospective study of dimethylsulfoxide in the treatment of inflammatory bladder disease. Br J Urol 1987;59:142-144.

10. Parsons CL, Schmidt JD, Pollen JJ. Successful treatment of Interstitial Cystitis with sodium pentosanpolysulfate. J Urol 1983;130:51-53.