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2007, Number 1

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Rev Med UV 2007; 7 (1)

Comaparative study of ferrocinetic in patients with chronic disease and pregnant women with hypochromic microcytica anemia

López MJJD, Blázquez MMSL, Blázquez DCR, González OSA, Carmona CDA, Domínguez TE
Full text How to cite this article

Language: Spanish
References: 13
Page: 22-26
PDF size: 651.15 Kb.


Key words:

Iron-Deficiency, Kinetic iron, Serum iron, Total Capacity of Fixation of the Transferrin (TCFT), Ferritine.

ABSTRACT

Introduction. 30% of the world-wide population, constituted by 4.500 million habitants, suffers of anemia and half of the cases is ferropenic; this is the most frequent cause of anemia in the world. The anemia of chronic disease (ACD) is the commonest between the hospitalized patients; one appears until in 50%, is the more frequent hematological abnormality in patients with cancer. Objective. To evaluate the existing differences in the iron kinetic in pregnant and patient with chronic disease that attended with hypochromic microcytica anemia. Material and method. Selected 270 clinical files of which 142 corresponded to pregnant in the third trimester of gestation and 128 to patients with chronic disease both populations with hypochromic microcytica anemia. Results. Of the two studied populations, 100 pregnant women (70.4%) presented serum iron below his limits inferior (50 mg/ dl) like 110 patients with chronic disease (85.9%); in the case of total capacity of fixation of the transf erring (TCFT), 115 pregnant women (80.9%) presented high levels to 350mg/dl, and 121 patients with chronic disease (94.5%) low levels to 300mg/dl; in the ferritine, 77 pregnant women (54.2%) presented low levels (smaller of 50mg/dl) and 89 patients with chronic disease (69.5%) high levels (higher 200mg/dl). Conclusion. In the pregnant women and the patients with chronic disease with hypochromic microcytica anemia, the kinetic iron is altered. Both populations presented low levels iron in the serum; not thus in the ferritine, where low levels in were embarrassed and high levels in patients with chronic disease; whereas to TCFT the opposite happened. The use of the kinetic iron as it proves to help in the diagnosis of Iron-Deficiency anemia is very useful, allows us to differentiate a ferropenic anemia (pregnancy) from an anemia of the chronic disease.


REFERENCES

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Rev Med UV. 2007;7