Velasco LMC, Chávez OJL

Language: Spanish
References: 25
Page: 55-64
PDF size: 82.42 Kb.

ABSTRACT

Aethiology and pathogenesis of Peripheral Diabetic Neuropathy were discussed and have not recognized exactly. Non invasive electrophysiological evaluation Blink Reflex permits differentiation between axon degeneration and demyelinating process, like complement of electrophysiologic evaluation of peripheral nerves. Purpose: 20 diabetic patients without symptoms of peripheral neuropathy were evaluated with BR and NCV. Methods: 20 diabetic patients were reviewed, 15 male and 5 female, with average age 55 years old. BR was performed bilaterally and motor conduction velocities of median, ulnar, peroneal and tibial nerves, and sensory nerve conduction in median, ulnar a sural nerves. Results: 95% had DMII a 5% DMI. 35% with less five years of evolution time, 35% with 5 to 10 years an 30% with › 10 years. BR was abnormal in 30%, 20% had alterations in afferent pathway and 10% in efferent pathway (p ‹ 0.05). Axonal degeneration was present in 70% (p= ‹ 0.05), 10% with axon degeneration and 10% with tibial and peroneal mononeuropathy. There were found alterations en median nerve (33%), ulnar nerve (20%), tibial nerve (50%). Prolonged sensory latencies were found in 25% of ulnar and median nerves, 50% in tibial nerve and 30% of sural nerve. 30% of the patients had abnormalities in BR and peripheral motor nerve conduction velocities. Conclusions: Sensory fibers of peripheral nerves and trygeminal nerve are more vulnerable than motor fibers in Diabetes Mellitus. BR is an evaluation that needs more investigation for determining its usefulness how diagnostic tool in polyneurophaty, afferent pathway is more sensitive than efferent pathway. There is a direct relationship between diabetes mellitus evolution time and peripheral axonal damage.

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