Carrillo ER, Ornelas AYS, Aguilar MS

Language: Spanish
References: 10
Page: 193-197
PDF size: 325.40 Kb.

ABSTRACT

Adult polycystic liver disease (APLD) is a rare condition with a prevalence of 0.05% to 0.13%. APLD is characterized by autosomal dominant inheritance and numerous hepatic cysts. Mutations in two distinct genes, PRKCSH and SEC63, are associated to liver cysts. The principal complications are bleeding, infection or compressive symtomatologi secondary to massive hepatic cyst disease. Ischemic hepatitis, also know as hypoxic hepatitis, is characterized by centrilobular liver cell necrosis and sharply increasing serum aminotransferase levels in a clinical setting of shock. The association between these two entities has not been reported. The aim of this paper is to describe the case of a patient with polycystic liver disease who developed ischemic hepatitis after hemorrhagic shock and review the principles of these two entities.

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