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Patología Revista Latinoamericana

2011, Number S1

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Patol Rev Latinoam 2011; 49 (S1)

Larynx angiomyolipoma or angiolipoma with abundant primary smooth muscle? Finding discussion

Muñoz AR, Carrera MEC

Language: Spanish
References: 10
Page: s47-s50
PDF size: 359.69 Kb.


ABSTRACT

Angiomyolipoma is a typical lesion of the kidney, although cases have been reported in extrarenal like lesions, it has been reported only a single case in larynx. This tumor shows three basic components: smooth muscle, blood vessels, thick-walled tortuous and mature adipose tissue and the consistent positive immunohistochemical marker HMB-45 in fourth histological component, called “perivascular epithelioid cells”. We report the case of a 71-year-old man, who had a history of intermittent dysphonia of 10 years of evolution. It was removed a vocal cord injury, with clinical consideration of squamous cell carcinoma. The histological analysis showed a lesion with abundant thick-walled vessels, smooth muscle and adipose tissue. Thus, it was performed immunohistochemistry with the possibility of extrarenal angiomyolipoma, being positive for CD34 and desmin but negative for HMB-45, leading to consider angiomyolipoma with abundant smooth muscle tissue.


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