Novoa-Vargas A, Sánchez-Bautista K, Coudillo-Luna I

Language: Spanish
References: 12
Page: 45-51
PDF size: 565.51 Kb.

ABSTRACT

The arrenoblastome is an ovary tumor with masculine hormone production, testosterone and other hormones. Other names are: stromatic tumor or gonadal stromatic tumor, also steroid cell tumor. They are rare tumors; represent 0.5% of all ovary tumors. It could be present in all age women groups, more frequently in young people. Most of times unilateral (95%), solids or quistic-solids. Anaplastic grade give them a malignity disease in 5 to 10 % cases. We report the case of a 35 year-old woman with clinical appearance of androgenism for ovary tumor, she was accepted for surgery, founded 7 liters of ascitis, produced for an ovary tumor, integral capsule, it produced masculine hormones. Histological study reported ovarian sex cord tumor, high grade, 30 cm size, integral capsule, all normally. Stage IC. Size and differential cellular grade need systemic chemotherapy. At the time of this report her tumoral marks are normal, and she has gradual diminution of virilizing characters produced for ovary tumor. Prognosis of the disease depends the grade of cell differentiation and stage in surgical-pathological events. Survival to five years stage I is approximate in 70 to 90% of the cases. Angular stone treatment is surgery. Disseminate cases, chemotherapy or radiotherapy most be considerate. Usually arrenoblastome has poor possibilities of dissemination and considering the early detection the histological grade of healthy is very high.

REFERENCES

1. Bulun SE, Adashi EY. The physiology and pathology of the female reproductive axis. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, editors. Williams Textbook of Endocrinology. 11th ed. Philadelphia: Saunders Elsevier, 2008, chap. 16.

2. Coleman RL, Gershenson DM. Neoplastic diseases of the ovary: screening, benign and malignant epithelial and germ cell neoplasms, sex-cord stromal tumors. In: Katz VL, Lentz GM, Lobo RA, Gershenson DM, editors. Comprehensive gynecology. 5th ed. Philadelphia: Mosby Elsevier, 2007, chap. 33.

3. Thrall MM, De Loia JA, Gallion H, Avril N. Clinical use of combined positron emission tomography and computed tomography (FDG-PET/CT) in recurrent ovarian carcinoma. Gynecol Oncol 2007;105:17-22.

4. Registro Histopatológico de Neoplasias en México 2000. Dirección General de Epidemiología. Secretaría de Salud. Consultado en: .

5. Fuentes Aguilar JE, Santos Lartigue A, Pérez Rosas ME, Lomas Flores A, Escobar Moreno AC. Arrenoblastoma (tumor de Sertoli-Leydig) reporte de un caso y revisión de la literatura. Patología Revista Latinoamericana 2009;47(2).

6. Rosai J. Female reproductive system. In: Ackerman’s surgical pathology. 8th ed. Vol. 2, chap. 19:1513-1518. St. Louis: Mosby-Year book.

7. Young RH, Clement PB, Scully RE. The ovary. In: Diagnostic surgical pathology. 3rd ed. Philadelphia: Sternberg, chap. 54:2351-2354.