Duarte TT

Language: Spanish
References: 8
Page: 373-375
PDF size: 202.06 Kb.

ABSTRACT

Wilson disease is an autosomal recessive disorder of copper metabolism. The Wilson disease protein is a copper transporting P-type ATPasa, ATP7B, whose malfunction results in the toxic acumulation of copper in the liver and brain, causing the hepatic and or neurological symptoms accompanying this disease. Chalation and zinc therapy are two treatments used for Wilson disease.

REFERENCES

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3. Mounif El-Youssef. Wilson disease. Mayo Clinic Proc. 2003; 78: 1126-36.

4. Nazer Hisham, Ede RJ, Mowat AP. Wilson`s disease: clinical presentation and use of prognostic index. Gut .1986; 27: 1377-81.

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7. Shaefer M, Schellenberg M, Merle Uta et al. Wilson protein expression, copper excretion and sweat production in sweat glands of Wilson disease patients and controls. BMC Gastroenterology. 2008; 29: 1-9.

8. Sullivan Ch, Chopdar A, Shun–Shin G. Dense Kayser Fleischer ring in asintomatic Wilson disease. Br J Ophthalmol. 2002; 86: 114-123.