Enriquez ÁRV

Language: Spanish
References: 5
Page: 61-65
PDF size: 213.78 Kb.

ABSTRACT

Objective. To know the morbidity and death of patients with surgical pulmonary valve replacement. Introduction. The purpose of this study is to evaluate the security and efficacy of Ketorolac/Tramadol drops by oral route as a treatment of nociceptive pain in 160 pediatric patients (16-year-old or younger).
Methods. This is phase III, prospective, randomized, and not comparative clinical trial to evaluate the Ketorolac/Tramadol drops combination orally each 12 hours, during 3 days. The pain was evaluated in 3 occasions by the clinical scale of pain, the faces scale and the monitoring of: cardiac rate, respiratory frequency, O₂ saturation, and observing signs as crying, anxiety and sweating.
Results. A significant reduction of pain was observed on the second visit, the postsurgical, burned and oncologic patients showed a decrease on pain of 49.48, 61.41 and 51.75% respectively. That tendency continued during the third visit, the reduction of pain on postsurgical, burned and oncologic patients was of 63.21, 60.53 and 80.67% respectively, with regard to second visit.
Discussion. The results showed that the tramadol/ketorolac combination is secure and effective in the treatment of postsurgical, oncologic and burning pain in children. In addition, a good safety profile was observed since only 8 mild adverse reactions were registered.

REFERENCES

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