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2009, Number 2

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Acta Cient Estud 2009; 7 (2)

Cardiovascular risk in patients with renal chronic failure in hemodialysis

Díaz M, Freire I, Flores E, Marulanda MI, Oviedo G
Full text How to cite this article

Language: Spanish
References: 14
Page: 76-84
PDF size: 85.45 Kb.


Key words:

Insuficiencia Renal Crónica (IRC), Hemodiálisis, Enfermedad Cardiovascular (ECV), Homocisteína.

ABSTRACT

Chronic Renal Failure (CRF) is a global problem of public health, and every year is registered an increase of his prevalence between 4-5%, also an important relation exists between CRF and cardiovascular disease, for which it is of big relevancy the study of traditional and not traditional factors of risk in these patients. Objective: Evaluate cardiovascular risk in adult patients with CRF in hemodialysis. Methodology: This investigation is a not-experimental, transverse study; 60 patients were evaluated with CRF in hemodialysis, the patients were evaluated at the “Centro Nefrológico Carabobo”, doing evaluations of their medical records, interviews, physical examinations and nutritional evaluations of the patients according to the Scale of Global Subjective Evaluation (GSE), determinations of plasmatic levels of hemoglobine, cholesterol, triglycerides and Homocysteine. With the gathered information Framingham’s Score was evaluated and it was correlated with the levels of Homocysteine, Cholesterol and triglycerides. Results: The treatment with hemodialysis prevailed in young adults; the most frequent causes are: primary nephropathy (31.7%), diabetic (28.3%) and hypertensive (23.3%); the average time in hemodiálisis was 2.6 years. The lipid alterations more frequent were: Low HDL-C (51.7%), and moderate ascent of triglycerides (25%). The presence of undernourishment (78.3%) and anemia (96.7%) allowed to predict a high level of Cardiovascular Risk, in contradiction with Framingham’s Score (5%) and levels of Homocysteine (36.7%). Conclusion: The patients with T-CRF must be considered a group of high risk, independently of the presence or not of traditional factors of risk.


REFERENCES

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  2. MSDS: Dirección de epidemiología y análisis estratégico; dirección de información social y estadísticas. Disponible en: www.msds.gov.ve/msds/direcciones_msds/Epidemiologia/Estadistica/Index . (Fecha de acceso: September 15 del 2008).

  3. National Institute of Health, National Institute of Diabetes and Digestive and Kidney Diseases. US Renal Data System, USRDS 2000 Annual Data Report. Bethesda, Md: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 2000. Disponible en: http://www.usrds.org/atlas_2000.htm. (Fecha de acceso: Septiembre 12 del 2008).

  4. National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification and stratification. Am J Kidney Dis. 2002; 39 (2 suppl 1): S1–S266.

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  6. Edwards M, Craven T, Burke G, Dean R, et al. Renovascular disease and the risk of adverse coronary events in the elderly. Arch Intern Med. 2005; 165:207-213.

  7. Harnett JD, Foley RN, Kent GM, et al. Congestive heart failure in dialysis patients: prevalence, incidence, prognosis and risk factors. Kidney Int. 1995; 47: 884–890.

  8. Sarnak, M.; Andrew, C. et all. Kidney Disease as a risk factor for development of cardiovascular disease. Circulation 2003;108:2154-2168

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  10. Pifer TB, McCullough KP, Port FK, Goodkin DA, Maroni BJ, Held PJ, Young EW: Mortality risk in hemodialysis patients and changes in nutritional indicators: DOPPS. Kidney Int 62:2238-2245, 2002 . (Fecha de acceso: Noviembre 21 del 2008).

  11. Foley RN, Parfrey PS, Harnett JD, et al. The impact of anemia on cardiomyopathy, morbidity and mortality in end-stage renal disease. Am J Kidney Dis 1996; 28:53.

  12. McClellan WM, Flanders WD, Langston RD, et al. Anemia and renal insufficiency are independent risk factors for death among patients with congestive heart failure admitted to community hospitals: a population-based study. J Am Soc Nephrol 2002; 13:1928.

  13. National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Managing Dyslipidemias in Chronic Kidney Disease. http://www.kidney.org/professionals/kdoqi/guidelines_cvd/guide13. (Fecha de acceso: Noviembre 21 del 2008).

  14. Osemwegie E, Emovon, MD. Cardiovascular disease in Hemodiálisis patients. Renal Week 2002.




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Acta Cient Estud. 2009;7