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Revista Salud Pública y Nutrición

Coordinación General de Investigación de la Facultad de Salud Pública y Nutrición y la Dirección General de Sistemas e Informática de la Universidad Autónoma de Nuevo León
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2011, Number 2

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Rev Salud Publica Nutr 2011; 12 (2)

Efecto de la actividad antiespasmodica del extracto metanolico del alga Oedogonium capillare (Linn) Kuetz sobre ileon de rata wistar

Vargas SRC, Pérez GRM, Figueroa TG
Full text How to cite this article

Language: Spanish
References: 12
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Key words:

antispasmodic activity, methanol extract, Oedogonium capillare.

ABSTRACT

The antispasm effect of methanol, chloroform and hexane extracts of the algae Oedogonium capillare (Linn.) Koetz was evaluated in an in Vitro preparation for an isolated organ. This was tested on the ileum of Wistar rats using acetylcholine and potassium chloride. For each of them, IC50 was determined. The methanol extract had a significant relaxation effect on the ileum in contrast with the other chloroform and hexane extracts which showed no activity. The methanol extract showed also a capability to inhibit contractions induced with KCl and acetylcholine; this antispasm effect might account for the use of this algae in traditional medicine.


REFERENCES

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  2. Hirn, K.E. 1960 Monographie der Oedogoniaceen. H.R. Engelmann (J. Cramer) and Wihildon & Wesley, New York. 52, 112-114.

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  11. Amos S., F. K Okwuasaba, K Gamaniel, P.Akah and C.Wambebe 1998 Inhibitory efect of the aqueous extract Pavetta crassipes leaves on gastrointestinal and uterine smooth muscle preparations isolated from rabbits, guinea pigs and rats. J. of Ethnopharmacol. 61: 209-213.

  12. Borrelli, F., N Borbone., C R.apasso, D. Montesano, S.De Marino, G.Aviello, G. Aprea and A. Izzo 2009 Potent relaxant effect of a Celastrus paniculatus extract in the rat and human ileum. J. of Ethnopharmacology.122:434-438




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Rev Salud Publica Nutr. 2011;12