Gutiérrez PRA, Flores MLÁ, Alonso MD, Mateos TH, Gaxiola GMO, Mejía ÁME

Language: Spanish
References: 8
Page: 199-202
PDF size: 199.92 Kb.

ABSTRACT

The related diseases associated with the application of biopolymer for cosmetic purposes have been described, but the physiopathology consequences are not well understood. Some of the most important complications and the increasing mortality are related to pulmonary disease. We are presenting two cases of acute pneumonitis due to liquid biopolymer application, 1,000 mL approximately, to the buttocks. Both patients were male transsexuals, in the mid-thirties. After the application the patients developed chest pain and dyspnea, with mild hypoxemia, peripheral consolidation areas and ground glass opacities diffuse in the CT scan. The treatment consisted in systemic steroids and oxygen supplementation with success clinical outcome and radiographic resolution. It is known that indiscriminate use of these substances, often of dubious source, may cause serious complications and can lead to a fatal resolution; the early diagnosis can improve the outcome of patients and the role of treatment with systemic steroids is uncertain.

REFERENCES

1. Zamora AC, Collard HR, Barrera L, Mendoza F, Webb WR, Carrillo G. Silicone injection causing acute pneumonitis: a case series. Lung 2009;187:241-244.

2. Narins RS, Beer K. Liquid injectable silicone: a review of its history, immunology, technical considerations, complications, and potential. Plast Reconstr Surg 2006;118(Suppl 3):77S-84S.

3. Pastor E, Andreu AL, Chiner E. Neumonitis aguda y síndrome de distrés respiratorio del adulto tras inyección subcutánea de silicona líquida. Arch Bronconeumol 2005;41:702-703.

4. Chastre J, Basset F, Viau F, Dournovo P, Bouchama A, Akesbi A, Gibert C. Acute pneumonitis after subcutaneous injections of silicone in transsexual men. N Engl J Med 1983;308:764-767.

5. Parikh R, Karim K, Parikh N, Han P, Daoko J, Shamoon FE. Case report and literature review: acute pneumonitis and alveolar hemorrhage after subcutaneous injection of liquid silicone. Ann Clin Lab Sci 2008;38:380-385.

6. Clark RF, Cantrell FL, Pacal A, Chen W, Betten DP. Subcutaneous silicone injection leading to multi-system organ failure. Clin Toxicol 2008;46:834-837.

7. Sanz-Herrero F, Casimiro-Calabuig E, López-Miguel P. Neumonitis aguda tras la inyección subcutánea de silicona líquida para mamoplastía en un transexual. Arch Bronconeumol 2006;42:205-206.

8. Gurvits GE. Silicone pneumonitis after a cosmetic augmentation procedure. N Engl J Med 2006;354:211-212.