2011, Number 3
Rev Cent Dermatol Pascua 2011; 20 (3)
Muñoz EVF, Valenzuela PGA
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ABSTRACTFixed drug eruption is a farmacodermia characterized by the recurrence of lesions in the same sites after reexposure to the causative agent. Objectives: Determine clinical characteristics of patients with genital fixed drug eruption, and identify associated drugs with this pathology. Patients and methods: A descriptive, observational, retrospective and transversal study of 69 cases of genital fixed drug eruption studied in Department of Dermatology and Mycology of the CIDOCS-UAS of Culiacán, Sinaloa, México, from 1 January 1999 to 31 August 2010. Results: 86.95% were male, between 21 to 40 years-old (73.91%), predominated erythematous spots with blisters in 27.53% of men and 8.69% in women; the most frequent site in men was the glans 52.81%, and in women the introitus vaginal 7.87%, the evolution was ‹ 1 month in 50.72%. The causative agent more common in men was trimethoprim sulfamethoxazole, and in women alprazolam, ibuprofen and trimethoprim-sulfamethoxazole. Conclusion: We identified 69 cases of genital fixed drug eruption, wich is more common in men related to 23 causative agents.