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Perinatología y Reproducción Humana

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Instituto Nacional de Perinatología
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2011, Number 3

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Perinatol Reprod Hum 2011; 25 (3)

Morbidity in the infant of diabetic gestational mother, at the Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes

Delgado-Becerra A, Casillas-García DM, Fernández-Carrocera LA
Full text How to cite this article

Language: Spanish
References: 22
Page: 139-145
PDF size: 127.02 Kb.


Key words:

Infant of diabetic mother, macrosomy.

ABSTRACT

Introduction: Gestational Diabetes (GD) is one of the pathologic conditions that most frequently complicate pregnancies and has influence in both the mother and child future as well. Family background of Diabetes Mellitus, obesity, fetal death and previous DG influence its development. Neonatal morbidity rises 23%, mainly characterized by respiratory, metabolic, hematological alterations injuries associated to the route of birth, macrosomy and asphyxia. Objective: To acknowledge the morbidity of infant of GD mother compared with a group of infant of mothers without such pathology among the population at the Instituto Nacional de Perinatología Isidro Espinosa de los Reyes. Methods: An observational, comparative, analytical study was done. In which two groups were integrated: one, the study group (infant of GD mother), and Control group (infant of mothers without such pathology), each with 144 patients, there was a research of maternal background and morbidity developed by the neonate. Statistical analysis included: measures of central tendency (mean, standard deviation, and confidence interval), for demographic variables, and t Student, Chi square and relative risk, with a confidence level of 95% for the comparison of both populations. Results: The following maternal background resulted with statistical significance: familiar Diabetes Mellitus (RR 2.10, IC 95% 1.28-3.43), obesity (RR 2.5, IC 95% 1.06-5.88) and fetal death (RR 9.33, IC 95% 2.9-30.01). DG A1 and B2 conformed 89.6% of the study group. The neonatal morbidity in the study group was 86.8%, more than double that of the control group (28.5%) (RR of 3.4, 95% CI 1.66-5.37), corresponding to 40.3% respiratory pathology, with a predominance of the Lung Adaptation Syndrome 31.9% (RR 2.87, 95% CI 1.53-5.38) physical injury (RR 2.08, 95% CI 1.00-4.32), congenital malformations (RR 3.0, 95% CI 1.15-7.79) and hematological disorders (RR 2.8, 95% CI 0.98-7.99). Metabolic changes were presented only in the study group within a 7.0%. There was not a single case of asphyxia in both groups. There was no statistical significance in terms of route of birth, gestational age and days of hospital stay when comparing the two groups. Conclusions: Among the population studied, the background of diabetes mellitus, obesity and fetal death in the pregnant woman are risk factors that contribute in the development of gestational diabetes. The morbidity of the infant of diabetic mother is above the data referred by the international literature, probably due to the fact that our institution is a third level of attention concentration center. Respiratory disorders were predominant, specifically the lung adaptation syndrome.


REFERENCES

  1. American Diabetes Association. Gestational diabetes mellitus, position statement. Diabetes Care 1999; 22: 574-6.

  2. World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications. Geneva: World Health Organization. 1999; 1-49.

  3. Jones WC. Gestational diabetes and its impact on the neonate. Neonatal Network 2001; 20: 17-23.

  4. Dickinson JE, Palmer SM. Gestational diabetes: pathophysiology and diagnosis. Semin Perinat 1990; 14: 2-11.

  5. Ramírez FR, Nazer J. Recién nacido hijo de madre diabética. Servicio de Neonatología. Universidad Católica de Chile 2001; 26: 192-98.

  6. Nazer J, García M. Malformaciones congénitas en hijos de madres con diabetes gestacional. Rev Med Chile 2005; 133: 547-54.

  7. García JH, Rodas LM. Morbilidad en el recién nacido con fetopatía diabética. Rev Med IMSS 2002; 40: 5-10.

  8. Cowett M et al. The infant of the diabetic mother. Neo Review 2002; 3: 173-89.

  9. Danglon BC. Los hijos de madres diabéticas. Rev Mexicana de Pediatría 2004; 71: 248-57.

  10. Mancillas AJ, Gómez UF. Diagnóstico y clasificación de la diabetes mellitus, conceptos actuales. Revista de Endocrinología y Nutrición 2002; 1: 63-8.

  11. Estadísticas del Instituto Nacional de Perinatología 2004-2005.

  12. Normas y Procedimientos de Neonatología del Instituto Nacional de Perinatología. 2003; 31-4.

  13. Belmar JC. Incidencia de diabetes gestacional según distintos métodos diagnósticos y sus implicaciones clínicas. Rev Chil Obstet Ginecol 2004; 69: 2-7.

  14. James LA, Waller DK. Maternal obesity, gestational diabetes and central nervous system birth defects. Epidemiology 2005; 16: 87-92.

  15. Nold LJ, Georgieff KM. Infants of diabetic mothers. Pediatr Clin North Am 2004; 51: 619-37.

  16. Sierra ID. Diabetes y embarazo. 2da Ed. Santafé de Bogotá: Ed. Kimpres Ltda. 1994: 115-28.

  17. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997; 20: 1183-196.

  18. Buchanan T, Xiang A, Kjos W, Lee P, Trigo E, Nader I, Bergner A, Palmer J, Peters R. Gestational diabetes: antepartum characteristics that predict postpartum glucose intolerance and type 2 diabetes in latino women. Diabetes 1998; 47: 1302-10.

  19. Davies DP. Some effects of gestational diabetes. Prince of Wales Hospital, Department of Pediatrics Chinese University. On The Fetus and Newborn Baby 1988; 10: 3450-55.

  20. Banting FN. Lecture 1980. Of pregnancy and progeny. Diabetes 1980: 1023-35.

  21. Perichart PO, Alonso VP, Ortega GC. Fisiopatología y atención nutricia de pacientes con diabetes gestacional. Ginecol Obstet Mex 2006; 74: 218-23.

  22. Oded L et al. The consequences of not treating infant of gestational diabetes mother. American Journal of Obstetrics and Gynecology 2005; 192: 989-97.




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C?MO CITAR (Vancouver)

Perinatol Reprod Hum. 2011;25