Guerrero LCL

Language: Spanish
References: 29
Page: 335-339
PDF size: 119.43 Kb.

ABSTRACT

This is a review of the nephrogenic systemic fibrosis related and preceded by the nephrogenic fibrosing dermopathy, an idiopathic disorder observed in renal patients, mostly in dialysis, associated to thrombosis and surgery. The dermatologic features are thickening and induration of the skin starting in lower extremities, eventually spreading to upper extremities and lower part of the abdomen, usually the face is spared. Scleral plaques and conjuntivitis are frequent. The skin biopsy shows thickened collagen bundles, mucine deposition and fibrocyte infiltration. It was considered a dermatological problem. When the liver, lungs, muscles: the organ involvement, was detected, the name became nephrogenic systemic fibrosis and progressively has been related to exposure to gadolinium the contrast agent used in magnetid resonance. Risk factors are well identified. There is not a consensus treatment. Pentoxyphyline has been used in Europe, experiementally for itsy anti-fibtrotiv properties. Prevention is encouraged and education for referring physicians and patients about the possibility of the complication of MRI is fundamental.

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