2011, Number 4
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Rev ADM 2011; 68 (4)
Dental bioengineering: Is this the future of dental treatment?
Romero JG, Aldape BBC
Language: Spanish
References: 17
Page: 169-174
PDF size: 112.25 Kb.
ABSTRACT
Since time immemorial, man has strived to restore the lost functionality of missing dental organs. The greatest dream of dentistry is to be able to replace the materials used today with biological cell-based materials with an identical or similar composition, so as to enable lost tissue to be regenerated or repaired. Recent publications have emphasized the use of induced pluripotent stem cells (iPSC) as a possible solution to the ever-controversial issue of obtaining and using such cells. This is just one of the many possibilities for future research that have become apparent. Since it is the most successful, the application of these techniques in the field of dentistry would be the best way to reach the coveted dream of restoring lost tissue. This is just one of the ways in which dental bioengineering is opening up new horizons in the hope of achieving better results that will have a positive impact on our population’s health.
REFERENCES
Koussoulakos DS. Et. Al. A curriculm Vitae of teeth: Evolution, Generation, Regeneration. International Journal of Biological Science. 2009; 5 (3): 226-43.
Crubézy E. False teeth of the roman world. Nature 1998; 392: 29 Westbroek P. A marriage of bone and nacre. Nature. 1998; 391: 861 ME. Ring. Historia ilustrada de la odontología. Barcelona. Doyma 1989.
Yu J. Current approaches and challenges in making a bio-tooth. Tissue engineering: Part B. 2008;14 (3):307-19.
Nait Lechguer A. Vascularization of Engineered teeth. Journal of Dental Research 2008; 87 (12): 1138-1143.
Sonoyama W. Et. Al. Mesenchymal Stem Cell-Mediated Functional Tooth Regeneration in Swine. PLo SONE. 2006 1(1): e79.
Kresbach PH. Dental and Skeletal Stem cells: potential celular therapeutics for craniofacial regeneration. Journal of Dental Education. 2002; 66 (6):766-73Harada H. New Perspectives on tooth development and the dental stem cell niche. Arch Histol. Cytol. 2004; 67 (1): 1-11.
Hochedlinger K. Your inner Healers. Scientific American 2010; 1:47-53.
Takahashi K. Yamanaka S. Induction of pluripotent Stem cells from mouse embryonic and adult fibroblast cultures and defined factors. Cell. 2006; 126: 663-76.
Okita k. Ichisaka T. Yamanaka S. Generation of germlinecompetent induced pluripotent stem cells. Nature. 2007; 448: 313-7 Yamanaka S. A fresh look at iPS cells. Cell. 2009;137: 13-7.
Park IH. Et Al. Reprogrammic of humand somatic cells to pluripotency with defined factors. Nature. 2008; 451: 141-6.
Sun N. Et Al. Feeder free derivation of induced pluripotent stem cells from adult human adipose stem cells. Proct Natl Acad. Science. 2009; 106: 15720-15725.
Loh YH. Et Al. Generation of induced pluripotent stem cells from human blood. Blood. 2009; 113: 5476-5479.
Kim JB. Direct reprogramming of human neural stem cells by OCT4. Nature 2009; 461: 649-653.
Aoi T. Et Al. Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science. 2008; 321 (58889): 699-702.
Stadfeld M. Et Al. Reprogramming of pancreatic beta cells into induced pluripotente stem cells. Curr Biol. 2008 (18); 890-4.
Miyoshi K. Et Al. Generation of human pluripotent stem cells from oral mucosa. Journal of Bioscience and Bioengineering. 2010; 110 (3): 345-350.
Huejing D. Et. Al. Application of induced pluripotent stem (iPSC) in periodontal tissue regeneration. Journal of Cellular Physiology 2010; 226 (1) 150-157