Campuzano-Maya G

Language: Spanish
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Page: 39-79
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Breath tests have been used in research laboratories for over 30 years. Originally these tests were based on substrates labeled with carbon 14(¹⁴C), a radioactive isotope, contraindicated in children and women in gestational age, and harmful for the environment, which is with carbon 13 (¹³C), a non-radioactive isotope, without contraindications in children and pregnant women, and not harmful for the environment. Breath tests, following the successful introduction of the breath test with ¹³C-urea in the diagnosis and management of Helicobacter pylori infection, have been gaining ground as a non-invasive option for the diagnosis and monitoring of liverdisease, as a substitute for liver biopsy in cirrhosis, in liver transplants, in the diagnosis and monitoring of diseases associated with pancreatic exocrine function, in the study of the functioning of the stomach, particularly in patients with gastroparesis, and in the determination of orocecal time, just to mention the most widely used clinical applications of this new technology. This module discusses the basics of these teste and describes the four most representative breath tests.