García CA

Language: Spanish
References: 0
Page: 30-31
PDF size: 77.25 Kb.

ABSTRACT

Vulvar cancer is a relatively rare malignancy (0.6%). In a comprehensive study, which estimated the burden of cancers of the vulva, including VIS and VIN, could estimate the incidence of this cancer by racial, ethnic and geographical location. Neoplasms of the vulva are believed to result from a multifactorial process that develops from at least two distinguishable entities. On the one hand, a pathway dependent on persistent infection with Human Papillomavirus High Risk (HR-HPV) and precursor lesions which are the classical lesions known as vulvar intraepithelial neoplasia (VIN). The second pathway, independent of HPV infection, seem associated with different lesions (VIN 3) and / or lichen sclerosus. A recent study including a total of 300 brushed the vulva, showed that 35% were positive for any HPV type. Importantly, we showed that type 16 was the most prevalent (6%), followed by HPV types 6, 61 and 66 with 4.7%, 3.7% and 3.3% respectively. The fact that lesions of the vulva / vagina with HR-HPV precede those of the cervix, or may be associated with specific viral infections rates, more important every day, the study of specific types of HPV in precancerous lesions and cancer of the vulva.