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2008, Number 2

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Rev Med Inst Mex Seguro Soc 2008; 46 (2)

Evaluation of Gastric Atrophy. Comparison between Sidney and OLGA Systems

Ramírez-Mendoza P, González-Angulo J, Ángeles-Garay U, Segovia-Cuevas GA
Full text How to cite this article

Language: Spanish
References: 14
Page: 135-139
PDF size: 214.40 Kb.


Key words:

atrophic gastritis, carcinoma, Helicobacter pylori.

ABSTRACT

Background: histopathologic identification of atrophy and metaplasia is decisive to stop the way of gastritis→carcinoma in patients with chronic gastritis.
Objective: to compare diagnostic concordance between Sidney system and the Operative Link on Gastritis Assessment (OLGA) system.
Methods: 120 consecutive biopsies were analyzed by general pathologists according to the Sidney system. All of them were evaluated by a second pathologist who used OLGA System. We employed kappa index to evaluate diagnostic concordance between the classifications.
Results: the clinical picture includes dyspepsia (94%), abdominal pain (50%), gastroesophageal reflux (30%), bleed of the upper digestive system (24%), and presence of Helicobacter pylori (47.5%). Four were diagnosed as atrophy by Sidney system and 26 cases with atrophy by OLGA system. The concordance between two classifications systems was too low (p = 0.05).
Conclusions: the atrophy diagnosis, between systems, had low concordance. The description of metaplastic atrophy in the OLGA system represents the only one difference. The non-metaplastic atrophy is the same for both classifications. Therefore, the general pathologist should include this evaluation more consistently using OLGA system.


REFERENCES

  1. Suerbaum S, Micheti P. Helicobacter pylori infection. N Engl J Med 2002;347(15):1175-1186.

  2. Pelayo-Correa. Human gastric carcinogenesis; a multistep and multifactorial process. First American Cancer Society award lecture on cancer epidemiology and prevention. Cancer Res 1992; 52:6735-6740.

  3. Pelayo-Correa. A human model of gastric carcinogenesis. Cancer Res 1988;48:3854-860.

  4. Solcia E, Fiocca R, Luinetti O, Villani L, Padovan L, Calestri D, et al. Intestinal and diffuse gastric cancers arise in a different background of Helicobacter pylori gastritis through different gene involvement. Am J Surg Pathol 1996;20(Suppl 1): S8-S22.

  5. Offerhaus GJ, Price AB, Haot J. Observer agreement on the gastric atrophy. Histopathology 1999;34:320-325.

  6. Aydin O, Egilmez R, Karabacak T, Interobserver variation in histopathological assessment of Helicobacter pylori gastritis. World J Gastroenterology 2003;9:2232-2235.

  7. Chen X, van der Hulst RW, Bruno MJ, van der Ende A, Xiao SD, Tytgat GN, et al. Interobserver variation in the histopathological scoring of Helicobacter pylori related gastritis. J Clin Pathol 1999;52(8):612-615.

  8. Fiocca R, Villani L, Cornaggia M, Tinelli C, Solcia E. Interobserver variation in the assessment of H. pylori gastritis. Gut 1996;39(Suppl 2):A104-A105.

  9. Andrew A, Wyatt JI, Dixon MF. Observer variation in the assessment of chronic gastritis according to the Sidney System. Histopathology 1994;25:317-322.

  10. Hala MT, Zimaity E, Graham DY, Al-Asi M, Malaty H, Karttunen J, et al. Interobserver variation in the histopathological assessment of Helicobacter pylori gastritis. Hum Pathol 1996; 27:35-41.

  11. Rugge M, Correa P, Dixon MP, Fiocca R, Hattori T, Lechago J, et al. Gastric mucosal atrophy: interobserver consistency using new criteria for classification and grading. Aliment Pharmacol Ther 2002; 16:1249-1259.

  12. Dixon MF, Genta RM, Yardley JH et al. Classification and grading of gastritis. The updated Sidney system. Am J Surg Pathol 1996;20:1161-1181.

  13. Rugge M, Meggio A, Pennelli G, Piscioli F, Giacomelli L, De Pretis G, et al. Gastritis staging in clinical practice: the OLGA staging system. Gut 2007;56:631-636.

  14. Genta RM. Recognizing atrophy: another step toward a classification of gastritis. Am J Surg Pathol 1996:20(Suppl):S23-S30.




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Rev Med Inst Mex Seguro Soc. 2008;46