2011, Number 4
Perinatol Reprod Hum 2011; 25 (4)
Méndez Y, Báez F, Villamediana P
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ABSTRACTThe development of anthropogenic activities has allowed environmental dispersion of heavy metals as cadmium; this event is related with decreased male fertility. This study was carried out with the aim of determine the effect of in vitro exposure of human spermatozoa to cadmium. Spermatozoa were incubated in presence of CdCl2, in concentrations of 2 ppm and 4 ppm, and motility, vitality, membrane integrity, sperm capacitation and sperm chromatin integrity was assessed. In vitro exposure to CdCl2 caused a significant effect on moderate motility pattern (p = 0.01) and immobile sperm (p $8249; 0.05) whereas it didn’t cause a significant effect on viability, membrane integrity, acrosome reaction, sperm chromatin condensation and sperm chromatin fragmentation. Cadmium caused a deleterious effect on sperm motility; nevertheless, it didn’t cause decrease on viability, membrane or chromatin structure alterations under the concentrations studied in vitro.