Estrada PGA, Márquez FM, González HE

Language: Spanish
References: 12
Page: 319-325
PDF size: 89.22 Kb.

ABSTRACT

A descriptive and cross-sectional study was carried out in 116 patients with oral leukoplakia, assisted in the Stomatology Department of the Specialties Polyclinic belonging to "Saturnino Lora Torres" Teaching Clinical Surgical Provincial Hospital in Santiago de Cuba, from June, 2007 to the same month of 2010, in order to evaluate the results of the clinical and histopathological diagnosis of this disorder and their relation to the smoking habit and subjective symptoms. The samples for biopsies were deposited in a glass flask with 10 % formol, they were fixed in 5 % formaline, they were processed through the classic technique of inclusion in paraffin and then they were colored with hematoxiline-eosine, through which the presence of cellular changes was confirmed. Male sex, the absence of these symptoms, the epithelial dysplasia and the hyperparakeratosis prevailed in the case material, as the most common epithelial changes, as well as the severe dysplasia in heavier smokers. On the bases of the detected transformations, investigations allowing to specify the biological and histological implications of this disease should be carried out.

REFERENCES

1. Warnakulasuriya S, Reibel J, Bouquet J, Dabelsteen E. Oral epithelial dysplasia classification systems: predictive value, utility, weaknesses and scope for improvement. J Oral Pathol Med. 2008;37(3):127–133.

2. Santana Garay JC. Prevención y diagnóstico del cáncer bucal en Cuba. La Habana, Editorial Ciencias Médicas; 2002.

3. Martínez-Sahuquillo Márquez A, Gallardo Castillo I, Cobos Fuentes MJ, Caballero Aguilar J, Bullón Fernández P. La leucoplasia oral. Su implicación como lesión precancerosa. Av. Odontoestomatol. 2008;24(1):33-44.

4. Carnesoltas Lázaro D, Domínguez Odio A, Frías Vázquez AI, Dutok-Sánchez CM, García Heredia G. Alteraciones citogenéticas bucoepiteliales en pacientes portadores de leucoplasia. Rev Mex Patol Clin. 2007;54(3):104-111.

5. Vázquez Álvarez R, Fernández González F, Gándara Vila P, Reboiras López D, García García A. Correlación clínico-patológica de la leucoplasia oral en una muestra de 54 pacientes. Medicina Oral, Patología Oral y Cirugía Bucal. 2011;16(1):15-20.

6. Cerero Lapiedra R, Baladé Martínez D, Moreno López LA, Esparza Gómez GC, Bagán JV. Leucoplasia verrugosa proliferativa: propuesta de criterios diagnósticos. Medicina Oral, Patología Oral y Cirugía Bucal. 2010;15(5):276-282.

7. Esparza Gómez GC. Valoración de los diferentes tratamientos empleados en la leucoplasia oral. Av Odontoestomatol. 2008;24(1):105-109.

8. Estrada Pereira GA, Zayas Simón OP, González Heredia E, González Alonso C, Castellanos Sierra G. Diagnóstico clínico e histopatológico de la eritroplasia bucal. MEDISAN. [Internet]. 2010 [citado 12 Ago 2011];14(4). Disponible en: http://bvs.sld.cu/revistas/san/vol_14_4_10/san03410.htm

9. García-Pola Vallejo MJ, Martínez Díaz-Canel AI, García Martín JM, González García M. Risk factors for oral soft tissue lesions in an adult Spanish population. Community Dent Oral Epidemiol. 2002;30(4):277-285.

10. 10.Warnakulasuriya S, Johnson Newell W, Van Der Wall I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med. 2007;36(10):575-80.

11. 11.Napier SS, Speight PM. Natural history of potentially malignant oral lesions and conditions: an overview of the literature. J Oral Pathol Med. 2008;37(1):1-10.

12. 13.Klaus Hönninger. Tratamiento alternativo no invasivo de la Leucoplasia y Estomatitis nicotínica. Lima: Ethnoline; 2008.