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2011, Number 4

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Rev Mex Med Fis Rehab 2011; 23 (4)

Lactobacillus acidophilus, bifidus bacterium in Spinal Cord Injury Patients with Neurogenic Bowel during rehabilitation

Castellanos-Valencia A, Berumen-Amor E, Martín-Ortiz G

Language: Spanish
References: 42
Page: 123-128
PDF size: 67.27 Kb.


ABSTRACT

Objective: Effectiveness of Lactobacillus acidophilus, and bifidus bacterium synbiotic synergistic bio-gel with agave tequilana Weber inulin in spinal cord injury patients with neurogenic bowel. Design: Non-randomized, controlled, blind, clinical trial. Method: Patients with neurogenic bowel, spinal cord injury in Rehabilitation, with signed informed consent were treated alternately with a synbiotic drug and sugar, evaluated with a questionnaire to investigate stool frequency, anthropometric measurements, diet, and bowel symptoms four weeks before and after treatment. Results: 64 patients were included. Synbiotic was given to 31 and sugar to 33. Age range: 1-22 years, 59% males. All had spinal cord injury at any level. Stool frequency average per week without treatment was 3.3/2.5 and postreatment with synbiotic and sugar 10.7/10.3 respectively. Pretreatment Bristol Stool Scale 1.7/1.5. Postreatment 3.4/3.8. We found significant differences in intestinal bleeding (p = 0.04), abdominal bloating (p = 0.01), decrease in diarrheal events (p ‹ 0.001) and abdominal pain (p = 0.002), all favorable for the synergic synbiotic and without adverse reactions. Conclusions: The synbiotic and sugar had similar clinical benefits in colonic transit. But only the synbiotic restored the ecosystem, improvement abdominal pain, bloating, diarrhea, and bleeding. Synergic synbiotic may reduce the chronic use of laxatives in spinal cord injury patients under treatment for neurogenic bowel.


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