2011, Number 4
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Patol Rev Latinoam 2011; 49 (4)
Clinical-pathological findings in children with duodenal nodules
Blanco RG, García CE, Velasco SF, Bernal RRM, López FK, Faure FA, Penchyna GJ, Valencia MP
Language: Spanish
References: 15
Page: 257-261
PDF size: 348.20 Kb.
ABSTRACT
Background: Hyperplasia of lymphoid tissue in duodenum has well established endoscopic and histological criteria, their presence in
children is a little common endoscopic finding with uncertain clinical significance.
Objective: To describe the clinical-pathological findings in children with nodular duodenum and to report if there is any association with
the causes commonly associated in children, such as immunity disorders, food allergy or
Giardia lamblia infestation.
Patients and methods: Patients with image showing nodular duodenal endoscopy studies, done at Children’s Hospital of Mexico during
a period of five years, were selected; biopsies from esophagus, stomach, duodenum were obtained, as well as rapid test for
H. pylori
detection, aspired from the second portion of duodenum for detection of
Giardia lamblia and 10 mL of blood for detection of
H. pylori and
IgA quantification.
Results: From the 20 cases studied, none showed serum nor by immunofluorescence altered IgA quantification.
Giardia lamblia was not
found either, and only one patient had lactose intolerance. Nine cases had follicular gastritis associated to
H. pylori.
Conclusions: This study shows a clear association between infection due to
H. pylori and nodular duodenum in children. However, its
presence makes to rule out other causes such as immunity disorders, food allergy and
Giardia lamblia infestation. Clinical impact of this
disease is little clear and represents a field for its future long-term research.
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