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2003, Number 2

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Neumol Cir Torax 2003; 62 (2)

Disseminated cryptococcosis in an immunocompetent patient.

Flores-Colín I, Pérez RA, Novelo-Retana V, Bonifaz AV
Full text How to cite this article

Language: Spanish
References: 30
Page: 96-101
PDF size: 105.81 Kb.


Key words:

Cryptococcus neoformans, immunocompetent host.

ABSTRACT

Cryptococcosis is an opportunist mycosis caused by Cryptococcus neoformans; that can occurs in health people and with exposure to pigeons also with a higher frequency in the immunocompromised host. We present a female 43 years old, with a subacute onset with neurologic and pulmonary compliances. Clinical and radiological data, showed a tumor located in the left side of the thorax diagnosed as cryptococoma wich was disseminated to central nervous system. The patient was not immunocompromised. She received treatment by 10 weeks with anphotericin B, fluconazole and fluocitocin; without response; with persistent tumor in thorax and positive Cryptococcus culture. Continues with antimicotic drugs with adequate response, and negative antigens in CSF.


REFERENCES

  1. Sarosi AG, Davies FS. Fungal Diseases of the Lung. 3rd Edition, USA. Lippincott Williams & Wilkins, Philadelphia 2000: 91-103.

  2. Niederman SM, Sarosi AG, Glassroth J. Respiratory infections. 2nd edition USA: Lippincott Williams & Wilkins, Philadelphia 2001: 527-530.

  3. Aberg AJ, Mundy ML, Powderly GW. Pulmonary Cryptococcosis in patients without HIV infection. Chest 1999; 115(3): 734-740.

  4. Vilchez RA, Linden P, Lacomis J et al. Acute respiratory failure associated with pulmonary Cryptococcosis in non AIDS patients. Chest 2001; 119(6): 1865-1869.

  5. Dismukes EW. Management of Cryptococcosis. Clin Infect Dis 1993; 17(Suppl 2): S507-512.

  6. Hajjeh RA, Conn LA, Stephens DS y cols. Cryptococcosis: population-based multistate active surveillance and risk factors in human immunodeficiency virus-infected persons. J Infect Dis 1999; 179: 449-454.

  7. Yuang SL, Pan ChJ, Chong JY et al. Direct determination of Cryptococcal antigen in transthoracic needle aspirate for diagnosis of pulmonary Cryptococcosis. J Clin Microb 1995; 33(6): 1588-1591.

  8. Nuñez M, Peacock EJ, Chin R. Pulmonary Cryptococcosis in the immunocompetent host: therapy with oral fluconazole: A report of four cases and a review of the literature. Chest 2000; 118(2): 527-534.

  9. Graybill RJ. Overwiew of management of fungal infections: Part 2. Clin Infect Dis 1993; 17(Suppl 2): S513-S514.

  10. Dismukes EW. Introduction to antifungal drugs. Clin Infect Dis 2000; 30: 653-657.

  11. Saag MS, Graybill RJ, Larsen RA y cols. Practice guidelines for the management of Cryptococcal disease. Infectious Diseases Society of America. Clin Infect Dis 2000; 30(4): 710-718.

  12. Driver JA, Saunders CA, Heinze LB et al. Cryptococcal pneumonia in AIDS: is cryptococcal meningitis preceded by clinically recognizable pneumonia? J Acquir Immune Defic Syndr Hum Retrovirol 1995; 9(2): 168-171 (Abstract).

  13. Kerkening TM, Duma BJ, Shadomy S. The evolution of pulmonary Cryptococcosis: clinical implications from a study of 41 patients with and without compromising host factors. Ann Inter Med 1981; 94: 611-616.

  14. Hammerman KJ, Powell KE, Christianson CS et al. Pulmonary Cryptococcosis: clinical forms and treatment. Am Rev Respir Dis 1973; 108: 1116-1121.

  15. Drew PA, Takezawa K. Pulmonary cryptococcosis and pituitary Cushing’s disease. Diagn Cytopathol 1988; 18(5): 365-367.

  16. Dromer F, Mathoulin S, Dupont B et al. Comparison of the efficacy of amphotericin B and fluconazole in the treatment of Cryptococcosis in human immunodeficiency virus-negative patients: retrospective analysis of 83 cases. French Cryptococcosis Study Group. Clin Infect Dis 1996; 22(Suppl 2): S154-S160.

  17. Van der Horst CM, Saag MS, Cloud GA y cols. Treatment of cryptococcal meningitis associated with the acquired immunodeficiency syndrome. NIAID Mycoses Study Group and AISD Clinical Trials Group. N Engl J Med 1997; 337: 15-21.

  18. Feldmesser M, Crees Y, Casadevall A. Dynamic changes in the morphology of Cryptococcus neoformans during murine pulmonary infection. Microbiology 2001; 147(Pt 8): 2355-2365.

  19. Schelenz S, Malhotra R, Sim RB et al. Binding of host collections to the pathogenic yeast Cryptococcus neoformans: human surfactant protein D acts as an aggluti nin for acapsular yeast cells. Infect Immun 1995; 63(9): 3360-3368.

  20. Kimura M, Kaufman L, Maekura S et al. Pulmonary Cryptococcosis due to a capsule deficient atrain confused with metastatic lung cancer. Mycopathologia 1997; 140(20): 65-8 (Abstract).

  21. Miller KD, Mican JA, Davey RT. Asymptomatic solitary pulmonary nodules due to Cryptococcus neoformans in patients infected with human immunodeficiency virus. Clin Infect Dis 1996; 23(4): 810-812.

  22. Tanaka K, Miyazaki T, Maesaki S et al. Detection of Cryptococcus neoformans gene in patients with pulmonary cryptococcosis. J Clin Microbiol 1996; 34(11): 2826-2828.

  23. Lacomis JM, Costello P, Vilchez R, Kusne S. The radiology of pulmonary cryptococcosis in a tertiary medical center. J Thorac Imaging 2001; 16(3): 139-148

  24. Kuo TH, Hsu WH, Chiang CD et al. Ultrasound-guided fine needle aspiration biopsy in the diagnosis of pulmonary cryptococcosis. J Formos Med Assoc 1988; 97(3): 197-203 (Abstract).

  25. Liaw YS, Yang PC, Yu CJ et al. Direct determination of cryptococcal antigen in transthoracic needle aspirate for diagnosis of pulmonary cryptococcosis. J Clin Microbiol 1995; 33(6): 1588-1591.

  26. Shijubo N, Fujishima T, Ooashi K et al. Pulmonary cryptococcal infection in an untreated patient with sarcoidosis. Sarcoidosis 1995; 12(1): 7174 (Abstract).

  27. Wu TT, Wang HC, Yang PC et al. Pulmonary cryptococcosis: manifestations in the era of acquired immunodeficiency syndrome. J Formos Med Assoc 1999; 98(9): 621-626 (Abstract).

  28. Wong CM, Lim KH, Liam CK. Massive pleural effusions in cryptococcal meningitis. Postgrad Med J 1999; 75(883): 297-298.

  29. Yamamoto Y, Maesaki S, Kakeya H et al. Combination therapy with fluconazole and flucytosine for pulmonary cryptococcosis. Chemotherapy 1997; 43(6): 436-441 (Abstract).

  30. Yew WW, Wong PC, Wong CF et al. Oral fluconazole in the treatment of pulmonary cryptococcosis in non-AIDS patients. Drugs Exp Clin Res 1996; 22(1): 25-28 (Abstract).




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Neumol Cir Torax. 2003;62