medigraphic.com
ISSN 1561-3011 (Electronic)

2011, Number 2

<< Back Next >>

Rev Cubana Invest Bioméd 2011; 30 (2)

Intestinal morphofunction in moderately malnourished rats

González SA, Velazco BL, Gámez FM, Mendéz HM

Language: Spanish
References: 12
Page: 271-279
PDF size: 374.69 Kb.


ABSTRACT

It was carried out an experimental study with 40 rats Wistar (20 belonged to the control group and the rest to the experimental one), in those that a model of nutritional restriction was developed to 75 % during 3 and 5 later weeks to the weaning where morfofunctional variables of the thin intestine were determined. It constituted objective of this work to determine the main alterations that take place in the intestinal morphofunction of the undernourished rats. The intestinal morphofunction in the undernourished animals of the 3rd week is affected and he/she spreads to recover when increasing the time of malnutrition. The morphology and functionality of the thin intestine are in correspondence in the results. The affectation that takes place is expressed in decrease of the weight, longitude, content of proteins and in the activity of one of the enzymes of the border in brush of the enterocite.


REFERENCES

  1. Ganong WF. Regulación de la función gastrointestinal. En: Fisiología Médica. 17ma ed. México: El Manual Moderno; 2000. p. 533-70.

  2. Anuario estadístico del MINSAP 2008. [Acceso el 23 Abr 2008]. Disponible en: http://bvs.sld.cu/cgibin/wxis/anuario/?IsisScript=anuario/iah.xis&tag5003=anuario&tag5021=e&tag6000=B&tag5013=GUEST&tag5022=2008

  3. Valdés S, Gómez A. Temas de Pediatría. Capítulo 8. La Habana: Ed Ciencias Médicas; 2006. p. 52-60.

  4. Lowry OH, Rose Broygh NJ, Farr AL, Randal RJ. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry. 1951;193:265-75.

  5. Atkinson WB. Studies on the preparation and recoloration of fucsin sulfurous acid. Stain Technology. 1952;27:153-60.

  6. Balcells A. La clínica y el laboratorio. 20ma. edición. Barcelona: Ed Interamericana-McGraw-Hill; 2005. p. 23-25.

  7. National Research Council. Guide for the Care and Use of Laboratory Animals. Publication n. 85-23 (rev). National Institutes of Health, Bethesda; 1985.

  8. Heller M. Protein-Energy malnutrition: there is still work to do, editorial. J Pediatr Gastroenterol Nutr. 2001;32:519-20.

  9. Gámez Fonseca M. Repercusiones del déficit nutricional sobre el funcionamiento del intestino delgado en ratas. La Habana: Instituto de Ciencias Básicas y Preclínicas "Victoria de Girón"; 1985.

  10. Dahlqvist A, Banas A, Stymne S, Sánches J, Cerdá-Olmedo E, Martinez-Force E. In: Sánches J, Cerdá-Olmedo E, Martínez-Force E (eds). Advances in Plant Lipid Research, Universidad de Sevilla. Seville, Spain. 1998. p. 211-214.

  11. Costa SM, Gomes TAT, Haapalainen E, Fagundes Neto U. Microscopia eletrônica de varredura no intestino delgado na diarréia persistente. Arq de Gastroenterol. 2000;34:89-94.

  12. Dudley Mary A, Wykes L, Dudley Alden W. Lactase Phlorizin Hydrolase synthesis is decreased in protein malnourished pigs. J Nutr. 2008;127:687-93.




2020     |     www.medigraphic.com