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2012, Number 2

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Bol Med Hosp Infant Mex 2012; 69 (2)

Borreliosis: recurrent fever due to spirochetes. Case report

Sotelo CN, Valencia MP
Full text How to cite this article

Language: Spanish
References: 11
Page: 121-125
PDF size: 218.87 Kb.


Key words:

borreliosis, spirochetemia, relapsing fever, antibiotics, doxycycline.

ABSTRACT

Background. Relapsing fever is a complex group of diseases caused by spirochetes of the genus Borrelia transmitted to humans by lice or ticks. The purpose of this study is to present a case of relapsing fever
Case report. A 12-year-old girl with no relevant clinical history was admitted with fever, headache, cervical adenitis, and thoracoabdominal exanthema. She had relapsing fever for 3 to 5 days with 15- to 21-day-intervals of apyrexia during the past 3 months. Laboratory exams were normal or negative including antibodies for Borrelia burdorferi. Peripheral blood smear showed spirochetes. She was treated with various antibiotics and finally doxycycline was added with a good response. The patient is asymptomatic and without sequelae 3 months after treatment.
Conclusion. In the case we reported, relapsing fever due to spirochetemia was made during the differential diagnosis. Due to the difficulty in identification, it is important to have a clinical suspicion of this type of infection.


REFERENCES

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  2. Escudero-Nieto R, Guerrero-Espejo D. Enfermedades producidas por Borrelia. Enferm Infecc Microbiol Clin 2005;23:232-240.

  3. Cutler SJ. Relapsing fever—a forgotten disease revealed. J Appl Micorbiol 2010;108:1115-1122.

  4. Brouqui P, Raoult D. Arthropod-borne diseases in homeless. Ann NY Acad Sci 2006;1078:223-235.

  5. Cutler SJ, Bonilla M, Singh R. Population structure of East African relapsing fever Borrelia spp. Emerg Infect Dis 2010;16:1076-1080.

  6. López JB, Porcella SF, Schrumpf ME, Raffel SJ, Hammer CH, Zhao M, et al. Identification of conserved antigens for early serodiagnosis of relapsing fever Borrelia. Microbiology 2009;155:2641-2651.

  7. Toledo A, Anda P, Escudero R, Larsson C, Bergstrom S, Benach JL. Phylogenetic analysis of a virulent Borrelia species isolated from patients from with relapsing fever. J Clin Micorbiol 2010;48:2484-2489.

  8. Gordillo-Pérez MG, Solórzano-Santos F. Enfermedad de Lyme. Experiencia en niños mexicanos. Bol Med Hosp Infant Mex 2010;67:164-176.

  9. Boyer KM, Munford RS, Maupin GO, Pattison CP, Fox MD, Barnes AM, et al. Tick-borne relapsing fever: an interstate outbreak originating at Grand Canyon National Park. Am J Epidemiol 1977;105:469-479.

  10. Whitney MS, Schwan TG, Sultemeier KB, McDonald PS, Billhart MN. Spirochetemia caused by Borrelia turicatae infection in 3 dogs in Texas. Vet Clin Pathol 2007;36:212-216.

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Bol Med Hosp Infant Mex. 2012;69