medigraphic.com
Colegio de Medicos y Cirujanos República de Costa Rica

2012, Number 602

<< Back Next >>

Rev Med Cos Cen 2012; 69 (602)

Tratamiento de la Neurología Postherpetica

Acón RJ

Language: Spanish
References: 13
Page: 189-192
PDF size: 181.40 Kb.


ABSTRACT

Varicella – zoster virus is a herpesvirus that causes two distinct clinical syndromes. Primary infection is manifested as varicella (chickenpox), a contagious and usually benign illness that occurs in epidemics among susceptible children. Subsequent reactivation of latent varicella-zoster virus in dorsal root ganglia results in localized cutaneous eruption termed: herpes zoster. (1 6 8) Postherpetic neuralgia is the most common complication in inmunocompetent patients. (6) The available therapies shown to be effective in managing neuropathic pain include anticonvulsivant drugs, tricyclic antidepressant drugs, opioids, topical lidocaine, and intrathecal methylprednisolone. (11)


REFERENCES

  1. Arguedas A. Herpes Zoster. Actualizacion Medica Periodica 2006: 65: 1-5.

  2. Arvin A. Aging, immunity, and the varicella zoster virus. New Engl J Med 2005; 352: 2266-7.

  3. Dubinsky R, Kabbani H. Practice Parameter: Treatment of postherpetic neuralgia. An evidence-Based report of the Quality Standards Subcommittee of the American Academy of Neurology. American Academy of Neurology 2004; 63: 959-965.

  4. Dworkin R, Corbin A, et al. Pregabalin fot the treatment of postherpetic neuralgia. A randomized placebo-controlled trial. Neurology 2003; 60: 1274-1283.

  5. Gilron I,Bailey J et al. Moprphine, Gabepentin, or Their Combination for Neuropathic Pain. N Engl J Med 2005;352: 1324-1334.

  6. Gnann J, Whitley R. Herpes Zoster. New Engl J Med 2002;347: 340-346.

  7. Jung B, Johnson R, et al. Risk factors for postherpetic neuralgia in patients with herpes zoster. American Academy of Neurology 2004; 62: 1545-1551.

  8. Kimberlin D, Whitley R. Varicella-Zoster Vaccine for Prevention of Herpes Zoster. New Engl J Med 2007; 356: 1338-1343.

  9. Mendell J, Sahenk Z. Painful Sensory Neuropathy. N Engl J Med 2003; 348: 1245-1255.

  10. Oxman M, Levin M, et al. A vaccine to prevente Herpes Zoster and Postherpetic Neuralgia in Older Adults. New Engl J Med 2005; 352: 2271-2284.

  11. Raja S, Haythornthwaite J. Combination therapy for Neuropathic Pain- Which Drugs, Which Combination, Which Patients?. N Engl J Med 2005; 352: 1373-1375.

  12. Raja S, Haythornthwaite J, et al. Opioids versus antidepressants in postherpética neuralgia. Neurology 2002; 59: 1015-1021.

  13. Rowbothman M, Harden N. et al. Gabapentin for the treatment of Postherpetic Neuralgia.A randomized controlled trial. JAMA 1998; 280: 1837-1842.




2020     |     www.medigraphic.com