Pantaleón BOS, Amaro PJ, Rodríguez VL, Pérez LD, Chirino DL, Borrás MM

Language: Spanish
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ABSTRACT

Objective: to make a preliminary clinical assessment of Nadroparin calcium injection for the treatment and prophylaxis of thrombotic venous disease.
Methods: through review of medical histories, a preliminary assessment was made in terms of tolerance and effect of, and complication from the use of 5 700 UI anti-Xa (0,6 mL) Nadroparin calcium injection in patients with deep venous thrombosis in limbs, and of 2 850 UI anti-Xa (0,3 mL) Nadroparin calcium, as prophylactic method, in patients under low oral anticoagulant treatment who were going to undergo some sort of invasive procedure.
Results: all the patients recovered satisfactorily. Symptoms and signs improved, there was good tolerance to the drug in all the cases, and neither hemorrhage nor repeated thrombosis occurred.
Conclusions: the two forms of the drug, that is, 2 850 UI anti-Xa (0,3 mL) Nadroparin calcium injection as well as 5 700 UI anti-Xa (0,6 mL) Nadroparin calcium were effective, tolerable and practically harmless in the treatment and the prophylaxis of thrombotic venous disease.