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2012, Number 1

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Gaceta Médica Espirituana 2012; 14 (1)

Meningeal cryptococcosis. Presentation of a case

Novoa LAM, García CJL, Barrios FMM, Hernández BE, Pérez CAC

Language: Spanish
References: 14
Page:
PDF size: 219.48 Kb.


ABSTRACT

Background: Cryptococcal meningitis is an opportunistic disease that re-emerged in recent decades, associated with immunosuppression. This disease can be ignored and undiagnosed if one does not have the knowledge and suspicion of its presence, a situation that causes confusion with other causes of meningitis and brings about therapeutic errors, prevents healing and causes complications or death in severe cases. Case presentation: A female black patient 75 year-old patient with a history of malaria comes to consultation due to loss of sensitivity and motility, and headache. She had diagnoses of AIDS and cryptococcal meningitis through the study of cerebrospinal fluid and various tests to detect HIV. Treatment with antifungal and antiretroviral drugs was prescribed. Conclusions: An accurate diagnosis and the combination of antifungal and antiretroviral drugs were effective in saving the patient’s life and regressing most of her neurological symptoms.


REFERENCES

  1. Goldman L, Ausiello D. Cecil. Tratado de Medicina Interna. 23ra ed. España: Eselvier SA; 2009.

  2. Beers M, Porter R, Jones T, Berkwits M. El Manual Merck. 11na ed. La Habana: Ecimed; 2007.

  3. Dromer F, Mathoulin PS, Launay O, Lortholary O. Determinants of Disease presentation and outcome during cryptococcosis: the Crypto A/D study. PLoS Med. 2007 Feb;4(2):e21. Available from: http://preview.ncbi.nlm.nih.gov/pmc/articles/PMC1808080/?tool=pubmed

  4. Harrison. Principios de Medicina Interna. 17a ed. New York: McGraw-Hill; 2010. Disponible en: http://www.harrisonmedicina.com/content.aspx?aid=3729665

  5. García JL, Novoa A M. Criptococosis. Una amenaza para pacientes inmunodeprimidos Gaceta Médica Espirituana 2011; 13(3). Disponible en: http://bvs.sld.cu/revistas/gme/pub/vol.13.(3)_15/p15.html

  6. Mu XD, Li RY, Wan Z, Wang GF, Liu P, et al. The diagnostic value of serum latex agglutination test for pulmonary cryptococcosis. Chinese. 2008 May;31(5):360-3 Avaliable from: http://www.ncbi.nlm.nih.gov/pubmed/18953961

  7. Lindsley MD, Mekha N, Baggett HC, Surinthong Y, Autthateinchai R, et al. Evaluation of a newly developed lateral flow immunoassay for the diagnosis of cryptococcosis. Clin Infect Dis. 2011 Aug;53(4):321-5. Avaliable from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148258/

  8. Leal AL, Faganello J, Fuentefria AM. Epidemiological profile of cryptococcal meningitis patients in Rio Grande do Sul, Brazil. Mycopathologia. 2008 Aug;166 (2):71-5. Available from: http://www.springerlink.com/content/80512 p61455q0654/

  9. Bicanic T, Wood R, Meintjes G, Rebe K, Brouwer A, Loyse A, et al. High-dose amphotericin B with flucytosine for the treatment of cryptococcal meningitis in HIV-infected patients: a randomized trial. Clin Infect Dis. 2008 Jul 1;47(1):123-30. Available from: http://cid.oxfordjournals.org/content/47/1/123.long

  10. Dromer F, Bernede Bauduin C, Guillemot D, Lortholary O. Major role for amphotericin Bflucytosine combination in severe cryptococcosis. PLoS One. 2008 Aug;3(8):e2870. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483933/?tool=pubmed

  11. Lawn SD, Harries AD, Anglaret X, Myer L, Word R. Early mortality among adults accessing antiretroviral treatment programmes in sub-Saharan Africa. AIDS. 2008;22:1897-1908. Available from: http://www.who.int/hiv/events/artprevention/lawn_early.pdf

  12. Harling G, Orrell C, Wood R. Healthcare utilization of patients accessing an African national treatment program. BMC Health Serv Res. 2007;7: 80. Available from: http://www.biomedcentral.com/1472-6963/7/80

  13. Guidelines for the prevention, diagnosis and management of cryptococcal meningitis and disseminated cryptococcosis in HIV-infected patients. South Afr J HIV Med. 2007;28:25-35. Available from: http://www.kznhealth.gov.za/medicine/cryptoguidelines.pdf

  14. Tyler Warkentien, MD1 and Nancy F. Crum-Cianflone, MD MPH1. An Update on Cryptococcosis Among HIV-Infected Persons. Int J STD AIDS. 2010 October; 21(10): 679–684. Avaliable from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134968/?tool=pmcentrez




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