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ISSN 1025-0255 (Electronic)

2012, Number 1

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AMC 2012; 16 (1)

Antimicrobial prophylaxis in orthopedics: report of 93 patients

Álvarez LA; García LY

Language: Spanish
References: 34
Page: 35-44
PDF size: 175.36 Kb.


ABSTRACT

Background: postoperative infection is a complication with a high social and economic cost which may reach sometimes the death of the patient, therefore the importance of preventing and treating this disease in time.
Objective: to evaluate behavior and results of the prophylactic antimicrobial therapy in patients treated in a basic working group.
Method: a descriptive observational study was conducted with 93 patients who were applied prophylactic antimicrobial therapy in the University Hospital Manuel Ascunce Domenech from December 2009 to July 2010.
Results: the average age was 43,5 years. A relationship between the sexes was about 2 to 1,4. The method was applied mostly in 28 patients with closed fractures which internal fixation was made. The cefazolin was the most used in 70,9 % of patients. Thirty-five patients showed one or more risk factors closely associated with infection, of them one suffered postoperative infection. Adverse reactions were found in 4.3 % of patients.
Conclusions: prophylactic antimicrobial therapy is effective in the prevention of postoperative infection.


REFERENCES

  1. Tunger O, Karakaya Y, Cetin CB, Dinc G, Borand H. Rational antibiotic use. J Infect Dev Ctries. 2009; 3(2):88-93.

  2. Zywiel MG, Johnson AJ, Stroh DA, Martin J, Marker DR. Prophylactic oral antibiotics reduce reinfection rates following two-stage revision total knee arthroplasty. Int Orthop. 2011; 35(1):37-42.

  3. Mammel J, Kmet L. Perioperative antibiotic administration in orthopaedic trauma: a quality assurance project. Orthop Nurs. 2010; 29(2):77-83.

  4. Assor M. Noncemented total knee arthroplasty with a local prophylactic anti-infection agent: a prospective series of 135 cases. Can J Surg. 2010; 53(1):47-50.

  5. Braxton CC, Gerstenberger PA, Cox GG. Improving antibiotic stewardship: order set implementation to improve prophylactic antimicrobial prescribing in the outpatient surgical setting. J Ambul Care Manage. 2010; 33(2):131-40.

  6. Burnett RS, Aggarwal A, Givens SA, McClure JT, Morgan PM. Prophylactic antibiotics do not affect cultures in the treatment of an infected TKA: a prospective trial. Clin Orthop Relat Res. 2010; 468(1):127-34.

  7. Calise F, Capussotti L, Caterino S, Delitala A, Terrazzi P. Perioperative antibiotic prophylaxis in adults. Outline of the principal recommendations. National reference guidelines. Minerva Anestesiol. 2009; 75(9):543-7.

  8. Cavanaugh DL, Berry J, Yarboro SR, Dahners LE. Better prophylaxis against surgical site infection with local as well as systemic antibiotics. An in vivo study. J Bone Joint Surg Am. 2009; 91(8):1907-12.

  9. Rico Licona C, Cariño Ortega C. The paradigm of prophylactic antibiotic therapy in orthopedic surgery. Acta Ortop Mex. 2009; 23(3):137-41.

  10. Meehan J, Jamali AA, Nguyen H. Prophylactic antibiotics in hip and knee arthroplasty. J Bone Joint Surg Am. 2009; 91(10):2480-90.

  11. de Beer J, Petruccelli D, Rotstein C, Weening B, Royston K. Antibiotic prophylaxis for total joint replacement surgery: results of a survey of Canadian orthopedic surgeons. Can J Surg. 2009; 52(6):229-34.

  12. Abubaker AO. Use of prophylactic antibiotics in preventing infection of traumatic injuries. Dent Clin North Am. 2009; 53(4):707-15.

  13. Marek CL, Ernst EJ. The new American Academy of Orthopedic Surgeons' recommendations regarding antibiotic prophylaxis: where's the evidence?. Spec Care Dentist. 2009; 29(6):229-31.

  14. Metcalf R, Johnson R. Surgical care improvement project and the orthopaedic patient. Orthop Nurs. 2009; 28(5):227-31.

  15. Sumiyama Y, Arima Y. Surgical site infection (SSI) and postoperative infection. Masui. 2010; 59(1):36-45.

  16. Morris AM, Howie S. Recommendations for antibiotics in patients with joint prosthesis are irresponsible and indefensible. J Can Dent Assoc. 2009; 75(7):513-5.

  17. Randelli P, Evola FR, Cabitza P, Polli L, Denti M. Prophylactic use of antibiotic-loaded bone cement in primary total knee replacement. Knee Surg Sports Traumatol Arthrosc. 2010;18(2):181-6.

  18. Cole LM. Prophylactic antibiotics: What's your game plan?. Nurs Manage. 2010; 41(4):46-7.

  19. Moriarty TF, Schlegel U, Perren S, Richards RG. Infection in fracture fixation: can we influence infection rates through implant design?. J Mater Sci Mater Med. 2010; 21(3):1031-5.

  20. Falagas ME, Alex ou VG, Peppas G, Makris GC. Do changes in antimicrobial resistance necessitate reconsideration of surgical antimicrobial prophylaxis strategies?. Surg Infect (Larchmt). 2009; 10(6):557-62.

  21. Hadzikadic-Gusic L, Agarwal S. Current prophylactic perioperative antibiotic guidelines in trauma: a review of the literature and outcome data. Bosn J Basic Med Sci. 2009; 9:46-53.

  22. Stefánsdóttir A, Robertsson O, W-Dahl A, Kiernan S, Gustafson P. Inadequate timing of prophylactic antibiotics in orthopedic surgery. We can do better. Acta Orthop. 2009; 80(6):633-8.

  23. Freeman AF, Holland SM. Antimicrobial prophylaxis for primary immunodeficiencies. Curr Opin Allergy Clin Immunol. 2009; 9(6):525-30.

  24. Lee H, Jung D, Yeom JS, Son JS, Jung SI. Evaluation of ceftriaxone utilization at multicenter study. Korean J Intern Med. 2009; 24(4):374-80.

  25. Jiménez-Álvarez A, Acosta-Gutiérrez P, León-Govea MA, Contreras-Mendoza EJ, Millán-Guerrero RO. Antibiotic therapy frequency in hospitalised patients and associated risk factors. Rev Salud Publica (Bogota). 2009; 11(2):247-55.

  26. O'Toole JE, Eichholz KM, Fessler RG. Surgical site infection rates after minimally invasive spinal surgery. J Neurosurg Spine. 2009; 11(4):471-6.

  27. Hsu C, Cheng SH. Practice guideline adherence and health care outcomes--use of prophylactic antibiotics during surgery in Taiwan. J Eval Clin Pract. 2009; 15(6):1091-6.

  28. Kim DH, Spencer M, Davidson SM, Li L, Shaw JD. Institutional prescreening for detection and eradication of methicillin-resistant Staphylococcus aureus in patients undergoing elective orthopaedic surgery. J Bone Joint Surg Am. 2010; 92(9):1820-6.

  29. Kuong EE, Ng FY, Yan CH, Fang CX, Chiu PK. Antibiotic prophylaxis after total joint replacements. Hong Kong Med J. 2009; 15(6):458-62.

  30. Alexiou VG, Ierodiakonou V, Peppas G, Falagas ME. Antimicrobial prophylaxis in surgery: an international survey. Surg Infect (Larchmt). 2010; 11(4):343-8.

  31. Prokuski L. Prophylactic antibiotics in orthopaedic surgery. J Am Acad Orthop Surg. 2008; 16(5):283-93.

  32. Langer M. Perioperative antibiotic prophylaxis in adults: the 2008 update of the Italian Guidelines. How can we as anesthetists contribute to the reduction of surgical site infections?. Minerva Anestesiol. 2009; 75(9):540-2.

  33. Thompson CA. Surgical antimicrobial prophylaxis improves through teamwork. Am J Health Syst Pharm. 2009;66(17):1516- 7

  34. Harness NG, Inacio MC, Pfeil FF, Paxton LW. Rate of infection after carpal tunnel release surgery and effect of antibiotic prophylaxis. J Hand Surg Am. 2010; 35(2):189-96




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