Schroeder-Ugalde IM, Xochipitécatl-Muñoz DJ, Castellanos-Hernández H, Cruz-García-Villa P

Language: Spanish
References: 11
Page: 162-166
PDF size: 465.12 Kb.

ABSTRACT

Background: Cryotherapy currently offers the patient a minimally invasive treatment option with low morbidity for localized prostate cancer (CaP). In this study we report the results obtained with the use of cryotherapy in the Hospital Central Sur de Alta Especialidad de PEMEX.
Material and methods: The case records of all patients operated on with cryotherapy for CaP at the Hospital Central Sur de Alta Especialidad de PEMEX were reviewed. Thirty-four patients were enrolled in the study and 24 of them had post-cryotherapy biopsies. Of those patients, 19 (79.1%) presented with negative biopsies and five (20.8%) were positive. The patients were classified in three groups according to prostate specific antigen (PSA), Gleason score, and clinical stage. Recurrence rates were 44.4%, 27.7%, and 56.1%, in the low, intermediate, and high-risk groups, respectively. Complications included 22 (64.7%) patients with impotency, four (11.8%) with incontinence, three (8.8%) with stricture, and two (5.9%) with tissue sloughing. There was no statistical significance between groups, but when analyzed separately, Gleason score was a risk factor for biochemical recurrence. However, comparative studies with large case series have yet to be carried out between cryotherapy and radical prostatectomy, and especially with other minimally invasive treatment modalities.
Conclusions: There are still many questions in relation to the follow-up of these patients, and prospective studies with long-term follow-up are needed in order to determine their progression.

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