medigraphic.com
SPANISH

Anales Médicos de la Asociación Médica del Centro Médico ABC

ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2000, Number 2

<< Back Next >>

An Med Asoc Med Hosp ABC 2000; 45 (2)

Changes in the intraocular pressure following long-term use of fluticasone propionate in the patients with rhinitis. A comparative study

Schimelmitz IJ, Bross SD, Arrieta GJ,Guzmán UR, Merikansky A, Hanenberg MC
Full text How to cite this article

Language: Spanish
References: 9
Page: 65-69
PDF size: 84.47 Kb.


Key words:

, Fluticasone propionate, intraocular pressure.

ABSTRACT

Objective: The objective of the study was to evaluate if the use of topical fluticasone propionate for the treatment of rhinitis provokes an elevation of the intraocular pressure. Material and methods: Design: It was a comparative, double blind, experimental, prospective and longitudinal study. Interventions: To measure the intraocular pressure by Goldman's tonometry of the patients at the third week, sixth week, three months, six months and one year of utilizing placebo versus fluticasone applied as topical nasal aerosol. Results: There were some modifications in the intraocular pressure in patients that utilized fluticasone propionate, but without exceeding the normal parameters and there was not a statistical significant difference between the groups. Conclusions: Fluticasone propionate is safe and does not cause an increment in the intraocular pressure.


REFERENCES

  1. Tasman W, Jaeger E. Duane’s foundations of Clinical Ophthalmology. Vol 2. Caps 6, 7. Philadelphia: JB Lippincott, 1994.

  2. Pipkorn U, Proud D, Schleimer R et al. Effect of systemic glucocorticoid treatment on human nasal mediator release after allergen challenge. J Allergy Clin Immunol 1986; 77 (suppl): 180.

  3. Howarth PH. The immunopharmacology of rhinitis. In: Nackay. Rhinitis mechanisms and management. UK: Royal Society of Medicine, 1989: 33-51.

  4. Cummings Ch, Nalebuff DJ. Otolaryngology head and neck surgery. 2nd ed. Philadelphia: CV Mosby, 1992: 651-660.

  5. Naclerio RM, Proud D, Togias AG et al. Inflammatory mediators in late antigen-induced rhinitis. N Engl J Med 1985; 313: 65-70.

  6. Michels MI, Smith RE, Hemlich EM. Adrenal suppression and intranasally applied steroids. Ann Allergy 1967; 25: 569-574.

  7. Tasman W, Jaeger E. Duane’s clinical ophthalmology. Vol 3. Caps 41, 47. Philadelphia: JB Lippincott, 1994.

  8. Opatowski I et al. Intraocular pressure elevation associated with inhalation and nasal corticosteroids. Ophthalmology 1995; 102: 177-179.

  9. Francisco J. Padilla de Alba. Oftalmología fundamental. México: Méndez Cervantes, 1983: 221-222.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

An Med Asoc Med Hosp ABC. 2000;45