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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2012, Number 08

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Ginecol Obstet Mex 2012; 80 (08)

Cotyledonoid Dissecting Leiomyoma of the Uterus. A Malignant-Looking Benign Tumor

Chávez MS, Arias GML, Silva LRM, Villagrán UJÁ
Full text How to cite this article

Language: Spanish
References: 6
Page: 528-533
PDF size: 186.96 Kb.


Key words:

cotyledonoid leiomyoma, uterine myomatosis, Sternberg tumor.

ABSTRACT

The cotyledonoid dissecting leiomyoma of the uterus, or Stenberg tumor, is a rare variant of a smooth muscle benign tumor, classified in the group presenting an unusual growth pattern; clinically, it affects women in reproductive age. We report the case of a 43 year-old woman, who turned up at the Centro Estatal de Atencion Oncologica (State Cancer Care Center) in Morelia, Michoacan, presenting abnormal uterine bleeding and uterine fibroid of major elements. When performing a palpatory bimanual exam, a loose uterus of approximately 7 by 6 inches was identified; it ached when moving. The laboratory tests reported normal parametriums; the ultrasound showed, however, uterine fibroids of major elements. The uterus was enlarged due to a tumor of exophytic growth, which resembles placental cotyledons extended over the uterine surface, composed by smooth muscle nodules that dissected the uterine wall, and with infiltrative appearance in parametriums and the myometrial wall. Despite this microscopic aggressive appearance, a number of ultrastructuctural studies and immunohistochemical techniques proved its benign nature. This can help patients who want to preserve fertility avoid radical surgery.


REFERENCES

  1. Mi-Jin K, Yoon-Ki P, Jae-Ho C. Cotyledonoid Dissecting Leiomyoma of the Uterus: A Case Report and Review of the Literature. J Korean Medical Sciences 2002;17:840-844.

  2. W. Cheuck, MBBS; John K. C. Chan, MBBS, FRCPath; John Y. S. Liu, MBBS,MRCOG. Cotyledonoid Leiomyoma A Benign Uterine Tumor With Alarming Gross Appearance. Arch Pathol Lab Med 2002;126: 210-213.

  3. Marquina Ibáñez I, Ríos Mitchell MJ, Pascual Llorente M, Fuertes Zárate A, Valero Palomero MI, Gimeno Esteras E. Leiomioma cotiledonoide disecante del útero. A propósito de dos casos y revisión de la literatura. Rev Esp Patol 2005;38:243-246.

  4. Roth LM, Reed RJ, Sternberg WH. Cotyledonoid dissecting leiomyoma of the uterus. The Sternberg tumor. Am J Surg Pathol 1996;20:1455-1461.

  5. Anil Misir, MD, FRCPC, Dean Daya, MD, MHA, FRCPC, FASCP, Monalisa Sur, MBBS, FCPath, MMed, FRCPath, FRCPC. Cotyledonoid Dissecting Leiomyoma of the Uterus (Sternberg tumour): A Clinicopathological Study of Six Cases. Canadian Journal of Pathology 2009;1:9-15.

  6. Lorenzo Preda, Stefania Rizzo, Maria Sole Prevedoni Gorone, Roberta Fasani, Angelo Maggioni, and Massimo Bellomi. MRI features of cotyledonoid dissecting leiomyoma of the uterus. Tumori 2009; 95:532-534.




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Ginecol Obstet Mex. 2012;80