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Federación Mexicana de Ginecología y Obstetricia, A.C.

2012, Number 08

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Ginecol Obstet Mex 2012; 80 (08)

Differential Diagnosis of Dandy-Walker Syndrome Different Presentations

Tobías GP, Gil MM, Valero BJ, Zapardiel I

Language: Spanish
References: 10
Page: 534-539
PDF size: 148.05 Kb.


ABSTRACT

Objective: Dandy-Walker syndrome is a set of abnormalities of the posterior fossa including three modalities: classic Dandy-Walker malformation, Dandy-Walker variant and mega-cisterna magna. Our objective is clarify the differential diagnosis among these entities.
Material and method: Descriptive and retrospective study of Dandy-Walker cases diagnosed at our Department during the last five years plus a review of the related Medical literature.
Results: Three cases of Dandy-Walker modalities are reported: one case of classic Dandy-Walker malformation, one case of Dandy-Walker variant, and one case of false Dandy-Walker. In the first two cases the patients underwent legal abortion, whereas in the last one a healthy male newborn was delivered in the week 38 of gestation.
Conclusions: Malformations in the posterior fossa, including Dandy-Walker syndrome, are still a challenge in prenatal diagnosis. Technical developments in imaging, such as in three-dimensional sonography and magnetic resonance, allow higher resolution and multiplanar images for an easier diagnose. There is a high rate of false positive, particularly before the 18 week of gestation. It is advisable not to establish a final diagnose before that week.


REFERENCES

  1. Gratacós E, Gómez R, Nicolaides K, Romero R, Cabero L. Medicina Fetal. 1a. edición. Madrid: Editorial Panamericana, 2007. pp. 177-204.

  2. Has R, Ermis H, Yüksel A, Ibrahimoğlu L, Yildirim A, Sezer HD, Başaran S. Dandy-Walker malformation: A review of 78 cases diagnosed by prenatal sonography. Fetal Diagn Ther 2004;19:342-347.

  3. Harper T, Fordham LA, Wolfe HM. The fetal Dandy-Walker complex: Associated anomalies, perinatal outcome and postnatal imaging. Fetal Diagn Ther 2007;22:277-281.

  4. Malinger G, Lev D, Lerman-Sagie T. The fetal cerebellum. Pitfalls in diagnosis and management. Prenat Diagn 2009;29:372-380.

  5. Limperopoulos C, Robertson RL, Estroff JA, Barnewolt C, Levine D, Bassan H, du Plessis AJ. Diagnosis of inferior vermian hypoplasia by fetal magnetic resonance imaging: Potential pitfalls and neurodevelopmental outcome. Am J Obstet Gynecol 2006;194:1070-1076.

  6. Phillips JJ, Mahony BS, Siebert JR, Lalani T, Fligner CL, Kapur RP. Dandy-Walker malformation complex: correlation between ultrasonographic diagnosis and postmortem neuropathology. Obstet Gynecol 2006;107:685-93.

  7. Shekdar K. Posterior fossa malformations. Semin ultrasound CT MRI 2011;32:228-241.

  8. Zalel Y, Gilboa Y, Gabis L, Ben-Sira L, Hoffman C, Wiener Y, Achiron R. Rotation of the vermis as a cause of enlarged cisterna magna on prenatal imaging. Ultrasound Obster Gynecol 2006;27:490-493.

  9. Paladini D, Volpe P. Posterior fossa and vermian morphometry in the characterization of fetal cerebellar abnormalities: a prospective three-dimensional ultrasound study. Ultrasound Obster Gynecol 2006;27:482-489.

  10. Kline-Fath BM, Calvo-García MA. Prenatal imaging of congenital malformations of the brain. Semin ultrasound CT MRI 2011;32:167-188.




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