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Órgano oficial de difusión de la Federación Mexicana de Patología Clínica, AC y de la Asociación Latinoamericana de Patología Clínica/Medicina de Laboratorio

2012, Number 4

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Rev Mex Patol Clin Med Lab 2012; 59 (4)

Detection of autoantibodies in the early diagnosis and prognosis of arthritis of recent beginning

Suárez ZR, Ramagli A, Duran F, Torrens A, López S

Language: Spanish
References: 9
Page: 207-211
PDF size: 30.28 Kb.


ABSTRACT

Background: Prevent and reduce the injury in rheumatoid arthritis has been the clinical focus in the last decade. A diagnosis in less than ninety days in the recent onset arthritis is essential for this purpose. Anticipate the evolutionary gravity to establish adequate treatment has been another challenge. Objective: To show through a retrospective analysis the sensitivity and specificity of an autoantibodies minimum panel established in 2011 at the National Institute of Rheumatology in patients with arthritis of recent onset. Results: We obtained sensitivity of 48.5% and a specificity of 98.2% in the first consultation date, both far superior to previous study protocols. Conclusions: Antibody selection was efficient, highly specific and had a useful diagnostic sensitivity.


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