2010, Number 3
PDF size: 50.30 Kb.
ABSTRACTObjective: to identify prognostic factors in the National Registry of Acute Coronary Syndromes.
Methods: patients in medical care units with acute ischemic coronary syndrome (AICS) according to the criteria of the American Heart Association/American College of Cardiology/European Society of Cardiology, considering the GRACE score (GS) were studied.
Results: there were 2389 patients, 28.9 % women and 71.1 % men, mean age 63 ±11.7 years; with AICS with ST-segment elevation (69.11 %) and 30.89 % with AICS without ST elevation. The average of GS was 168. A GS › 150 points in patients with AICS without ST elevation was associated with recurrent ischemia or angina (RR = 1.4, p = 0.05), left ventricular failure (RR = 3.1, p ‹ 0.0001), stroke (RR = 2.9, p = 0.004) and arrhythmias (RR = 2.7, p ‹ 0.0001). The patients with AICS with ST-segment elevation were associated with death (RR = 1.6, p = 0.01), reinfarction (RR = 1.7, p = 0.001), recurrent ischemia (RR = 1.2, p = 0.04), left ventricular failure (RR = 3.4, p ‹ 0.001), stroke (RR = 3.9, p ‹ 0.001) and arrhythmias (RR = 2.3, p ‹ 0.001). Fibrinolytic therapy was used in 40.2 %. There was a negative correlation between GS and fibrinolytic therapy (r –0.04, p = 0.04).
Conclusions: the AICS with ST-segment elevation is more frequent and have a high GS.
Elbarouni B, Goodman SG, Yan RT, Welsh RC, Kornder JM, Deyoung JP, et al; Canadian Global Registry of Acute Coronary Events (GRACE/ GRACE(2) Investigators. Validation of the Global Registry of Acute Coronary Event (GRACE) risk score for in-hospital mortality in patients with acute coronary syndrome in Canada. Am Heart J 2009; 158(3):392-399.