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2010, Number 4

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Rev Med Inst Mex Seguro Soc 2010; 48 (4)

A H1N1 influenza infection in pregnant patients

Bello-Carrera R, Romero-López Z, Ochoa-Vázquez MD, Reyes-Calderón H, Rico-Méndez FG

Language: Spanish
References: 22
Page: 399-404
PDF size: 54.00 Kb.


ABSTRACT

Background: despite the severity of infection with influenza virus, little has been reported about its presence in pregnant women. Objective: to communicate our experience on influenza virus H1N1 in pregnant women.
Methods: we conducted a retrospective cohort study, on 16 hospitalized patients with diagnosis of pregnancy, and probable or confirmed case of infection with H1N1 influenza virus. Suspected case: sudden onset of respiratory infectious process, in 2009, in Mexico City. All cases underwent to fast detection test and subsequently requested confirmatory by PCR test. Discharge criteria: clinical improvement, PaO2 above 60 mm Hg and absence of bilateral consolidation on chest radiographs. Severity criteria: type I respiratory failure (PaO2 ‹ 50 mm Hg) who required mechanical ventilatory support, radiographic pattern compatible with multisegmental pneumonia and PaO2/FiO2 ‹ 200 mm Hg.
Results: the pregnant patient mortality was of 4.25 %. The average age was 25.8 years, with 24.13 weeks of gestation with 5.6 days average in hospitalized stay. The main co-morbidity was obesity.
Conclusions: the fatal cases were those with longer time of evolution and late diagnosis.


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