Pérez-León JA, Lane BR

Language: Spanish
References: 16
Page: 9-18
PDF size: 336.98 Kb.

ABSTRACT

A special group of retinal ganglion cells contains the photopigment melanopsin which makes these cells intrinsecally photosensitive. These cells are the photoreceptors described most recently in the retina (ipRGC). Behavioral, physiological and knocking out experiments have shown that ipRGC participate in a series of functions not related with vision, collectively known as extravisual functions of retina, the most prominent of these being photosincronization of the circadian clock. It still remains to described the phototransduction mechanism started by melanopsin and the cell-cell interactions that could modulate the ipRGCs functions. Hence, the discovery of these cells has opened a new research field within sensory physiology.

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