Muñiz HS, Mondragón FR

Language: Spanish
References: 15
Page: 52-58
PDF size: 291.82 Kb.

ABSTRACT

Toxoplasmosis is a worldwide disease that does not distinguish genera, race or geographical distribution. It affects ~30% of the world population and is caused by the intracellular obligate protozoan parasite Toxoplasma gondii. To date there are neither vaccines nor treatments to eliminate it when is located in its intracellular stage. Toxoplasma invades any cell by an active invasion process involving motility and molecular secretion. Its success as an invasive organism resides on its high trans-epithelial migration capability reaching privileged organs such as brain, eye and placenta in pregnant women. To date the mechanisms of cell recognition and chemotactic attraction that determine its migration and tissue dissemination are still unknown.

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