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Órgano Oficial del Instituto Nacional de Pediatría
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2012, Number 5

Acta Pediatr Mex 2012; 33 (5)

Infiltration of both optic nerves in acute lymphocytic leukemia. Report of a case

Arias-Cabello B, Ordaz- Favila JC, Juárez-Echenique JC
Full text How to cite this article

Language: Spanish
References: 6
Page: 236-238
PDF size: 183.99 Kb.


Key words:

Acute lymphocytic leukemia, infiltration optic nerve, peripapilar serous detachment, retina.

ABSTRACT

Background. Acute lymphocytic leukemia is the most common type of pediatric cancer (70%). Among its many presentations, ocular manifestations vary from conjunctivitis and anterior segment alterations to leukemic retinopathies and retina detachment. Leukemic infiltration of the optic nerve is unusual; its presence has a poor prognosis.
Case report. We present a case of a seven year-old boy with acute lymphocytic leukemia evaluated by the Ophthalmology Service with a 5 day history of sudden loss of vision. Examination of the eye fundi showed a white infiltrative lesion on both optic nerves accompanied with peripapilar serous retina detachment.


REFERENCES

  1. Mateo J, Abarzuza R, Nuñez E, Cristóbal JA. Infiltración bilateral del nervio óptico en un caso de leucemia aguda linfoblástica de células T en remisión. Arch Soc Esp Oftalmol 2007;82:167-70.

  2. Campos-Campos LE, Mendoza-Altamirano L, Pérez-Casillas RX, Beauregard-Escobar AM, Calderón Alvarado LM. Alteraciones oculares en pacientes pediátricos con leucemia aguda. Rev Mex Oftalmol 2004;78(6):287-90.

  3. Kincaid MC, Green WR. Ocular and orbital involvement in leukemia. Survey Ophthalmol 1983;27(4): 211-32.

  4. Mayo GL, Carter JE, McKinnon SJ. Bilateral optic disk edema and blindness as initial presentation of acute lymphocytic leukemia. Am J Ophthalmol 2002;134(1):141-2.

  5. Schocket LS, Massaro-Giordano M, Volpe NJ, Galetta SL. Bilateral optic nerve infiltration in central nervous system leukemia. Am J Ophthalmol 2003;135(1):94-6.

  6. Lin YC, Wang AG, Yen MY, Hsu WM. Leukaemic infiltration of the optic nerve as the initial manifestation of leukaemic relapse. Eye 2004;18:546–50.




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Acta Pediatr Mex. 2012;33