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2012, Number 5

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Med Int Mex 2012; 28 (5)

Diabetes Insipidus and Fever as Unusual Presentation of Langerhans Cell Histiocytosis. Case Report And Review of the Literature

Villalobos SJA, Tijerina LJC, Cuevas LLF, García ZT, González CE, Rodríguez HH
Full text How to cite this article

Language: Spanish
References: 12
Page: 516-521
PDF size: 265.13 Kb.


Key words:

Histiocytosis, proliferation of cells of the mononuclear phagocyte system.

ABSTRACT

Histiocytosis is defined as a heterogeneous group of diseases of unknown cause characterized by the proliferation of cells of the mononuclear phagocyte system (MPS). Few diseases are as confusing as the so-called histiocytosis, with an incidence of 4-8 per million and characterized by being localized or disseminated disease affecting multiple organs and systems, predominantly in childhood and even less common in young adults. In those who survive the acute illness his estimate of survival is 10 years in 77%.


REFERENCES

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  2. Nanduri VR, Bareille P, Pritchard J, Stanhope R. Growth and endocrine disorders in multisystem Langerhans’ cell histiocytosis. Clin Endocrinol (Oxf ) 2000;53:509-515.

  3. Nanduri VR, Lillywhite L, Chapman C, et al. Cognitive outcome of long-term survivors of multisystem Langerhans cell histiocytosis: a single-institution, cross-sectional study. J Clin Oncol 2003;21:2961-2967.

  4. Stepp SE, Dufourcq-Lagelouse R, Le Deist F, et al. Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Science 1999;286:1957-1959.

  5. Treatment Protocol of the Third International Study for Langerhans cell histiocytosis (LCH-III) [consultado 15/04/2006]. Disponible en: http://www.histio.org/society/protocols/trialsprotocols. shtml.

  6. Writing Group of the Histiocyte Society. (Chu T, D Angio GJ, Favara B, Ladish S, Nsbit M & Pritchard J.) Histiocytosis syndromes in children. Lancet 1987;1:208-209.

  7. Kaltasas GA, Powles TB, Evanson J, Plowman PN, Drinkwater JE, Jen- kins PJ, et al. Hypotalamo-Pituitary Abnormalities in Adult Patients with Langerhans Cell Histiocytosis: Clinical, Endocrinological and Radiologi- cal Features and Response to Treatment. J Clin Endocrinol Metabol 2000;85:1370-1376.

  8. Islinger RB, Kuklo TR, Owens BD, Horan PJ, Choma TJ, Murphey MD, et al. Langerhans Cell Histiocytosis in Patients Older Than 21 years. Clin Orth Related Res 2000;379:231-235.

  9. Gadner H, Grois N, Arico M, Broadbent V, Ceci A, Jakobson A, et al., for the Histiocyte Society. A randomized trial of treatment for multisystem Langerhans cell histiocytosis. J Pediatr 2001; 138:728-734.

  10. Hurwitz CA, Faquin WC. Weekly Clinicopathological Exercises: Case 5-2002: A 15-Year-Old Boy with a Retro-orbital Mass and Impaired Vision. N Engl J Med 2002;346:513-520.

  11. Henter J, Karlen J, Calming U, Bernstrand C, Andersson U, Fadeel B. Successful Treatment of Langerhans-Cell Histiocitosis with Etanercept. New Engl J Med 2001;345:1577-1578.

  12. Arzoo K, Sadeghi S, Pullarkat V. Pamidronate for Bone Pain from Osteolytic Lesions in Langerhans Cell Hisiocytosis. N Engl J Med 2001;345:225.




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Med Int Mex. 2012;28