medigraphic.com
SPANISH

Perinatología y Reproducción Humana

ISSN 0187-5337 (Print)
Instituto Nacional de Perinatología
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2012, Number 2

<< Back Next >>

Perinatol Reprod Hum 2012; 26 (2)

Congenital malformations as a cause of hospitalization in a Neonatal Intensive Care Unit

Salinas-Torres VM, Gutiérrez-Padilla JA, Aguirre-Jáuregui OM, Angulo-Castellanos E
Full text How to cite this article

Language: Spanish
References: 9
Page: 83-89
PDF size: 108.14 Kb.


Key words:

Congenital malformations, neonatal, prevention, mortality.

ABSTRACT

Introduction: Congenital malformations (CM) are a major public health problem and the leading cause of death in children; representing 20% of infant mortality in the first year of life. Objective: To evaluate the contribution of CM as a cause of hospitalization in a Neonatal Intensive Care Unit. Material and methods: We performed a retrospective, observational, transversal and descriptive study, in which we reviewed the medical records of 2,907 neonates, which entered the External Service of Neonatal Intensive Care (UCINEX) of the Hospital Civil de Guadalajara “Fray Antonio Alcalde”, in the period 2005-2009 with the diagnostic of congenital malformations (CM) according to the WHO ICD-10. Statistics: measures of central tendency and percentages were done. Results: Two hundred ninety five infants (10.14%) had CM, 67% male and 33% female. CM myelomeningocele was the most frequent (12.9%). The gastrointestinal tract was the most affected with 27.4% of CM, chromosomal abnormalities generated more days of hospitalization (20.5 ± 5.5 days), the cardiovascular system showed 34.2% of deaths. The overall mortality was 14.2%; 60% of CM was treated surgically and 64.5% of the mothers of these infants were living in the metropolitan area of Jalisco State. Conclusions: Knowledge of the contribution of CM to neonatal mortality is important for the integration of preventive measures and plan effective strategies for its prevention, identify their causes and establish treatment. This information highlights the importance of further study of early recognition of the morbidity and mortality in the pediatric population.


REFERENCES

  1. Ortiz AMR, Flores FG, Cardiel MLE, Luna RC. Frecuencia de malformaciones congénitas en el área de neonatología del Hospital General de México. Rev Mex Pediatr 2003; 70: 128-31.

  2. Sadler TW. Tercer mes al nacimiento: el periodo fetal y los defectos congénitos. En: Sadler TW, ed. Langman, embriología médica con orientación clínica. 8ª edición. España: Editorial Médica Panamericana; 2002: 109-31.

  3. Gómez-Alcalá AV, Rascón-Pacheco RA. La mortalidad infantil por malformaciones congénitas en México: un problema de oportunidad y acceso al tratamiento. Rev Panam Salud Pública 2008; 24: 297-303.

  4. Zubieta RB, Sánchez MP, Castillo CRA. Enfermedades genéticas y defectos al nacimiento. Impacto en la morbilidad y mortalidad pediátrica. Acta Pediatr Mex 2009; 30: 220-5.

  5. Scriver CR, Neal JL, Saginur R, Clow A. The frequency of genetic disease and congenital malformation among patients in a pediatric hospital. Can Med Assoc J 1973; 108: 1111-5.

  6. Yoon PW, Olney RS, Khoury MJ, Sappenfield WM, Chavez GF, Taylor D. Contribution of birth defects and genetic diseases to pediatric hospitalizations. A population-based study. Arch Pediatr Adolesc Med 1997; 151: 1096-103.

  7. Stevenson DA, Carey JC. Contribution of malformations and genetic disorders to mortality in a children’s hospital. Am J Med Genet A 2004; 126A: 393-7.

  8. Lialiaris T, Mantadakis E, Kareli D, Mpountoukas P, Tsalkidis A, Chatzimichail A. Frequency of genetic diseases and health coverage of children requiring admission in a general pediatric clinic of northern Greece. Ital J Pediatr 2010; 36: 9.

  9. Clasificación Internacional de Enfermedades 10 CIE 10 [homepage on the Internet] [updated 2012 feb 10]. Disponible en: http://apps.who.int/classifications/icd10/browse/2010/en#/XVII




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Perinatol Reprod Hum. 2012;26