2012, Number 4
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Rev ADM 2012; 69 (4)
Antibiotic therapy in general practice dentistry.
Moreno VAP,Gómez CJF
Language: Spanish
References: 20
Page: 168-175
PDF size: 168.70 Kb.
ABSTRACT
Odontogenic infection management should aim to
reduce, both quantitatively and qualitatively, the size of
the inoculum population. However, many questions
have been raised regarding the use of antibiotics in
general dentistry; whilst there is information that
supports its empirical use, such information does not
take into account the pharmacokinetic and
pharmacodynamic properties assessed in clinical trials.
The aim of this study is to determine the antibiotic
management of odontogenic infections in general
practice dentistry. Various international scientific
publications published between 2001 and 2011 were
reviewed, involving articles describing the infection
management and general practice procedures
associated with the particular pharmacological
characteristics of the drugs used and their efficacy
against the main oral pathogen recognized in
microbiological research. Odontogenic infections that
could require antibiotic treatment include pulpitis,
periapical abscesses, ulcerating necrotizing gingivitis,
pericoronitis, perri-implantitis, and aggressive
periodontitis.
Penicillins such as amoxicillin, amoxicillin with
clavulanic acid, phenoxymethylpenicillin, and
benzylpenicillin are the antibiotic drugs of first choice
in the treatment of oral infections. Where patients are
allergic to beta-lactam antibiotics, the drugs of first
choice include lincosamides, clindamycin, macrolides,
azithromycin and clarithromycin, tetracycline,
doxycycline, fluroquinolones, and moxifloxacin, along
with quinolones and ciprofloxacin. Metronidazole is
particularly recommended, it being an active drug
against anaerobic bacteria
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