2007, Number 2
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ABSTRACTThe transport of glucose across the plasma membrane of mammalian cells represents one of the most important nutrient transport events since this sugar plays a central role in cellular homeostasis and metabolism. Glucose enters the cells through two types of carrier proteins, the sodium - coupled glucose transporters (SGLT) and glucose transporter facilitators or carriers (GLUT). This review shows the principal molecular, biochemical and functional properties of each transporter.
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Godoy A, Ulloa V, Rodriguez F, Reinicke K, Yanez AJ, Garcia M de L, Medina RA, Carrasco M, Barberis S, Castro T, Martinez F, Koch X, Vera JC, Poblete MT, Figueroa CD, Peruzzo B, Perez F, Nualart F (2006) Differential subcellular distribution of glucose transporters GLUT 1-6 and GLUT 9 in human cancer: Ultrastructural localization of GLUT 1 and GLUT 5 in breast tumor tissues. J Cell Physiol 207:614 - 627.